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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
METHYL BROMODICHLOROACETATE METHYL BROMODICHLOROACETATE 20428-76-6 C3H3BrCl2O2
MYCOPHENOLIC ACID-D3 MYCOPHENOLIC ACID-D3 1185242-90-3 C17H20O6
BROMBUTEROL HYDROCHLORIDE BROMBUTEROL HYDROCHLORIDE 21912-49-2 C12H18Br2N2OHCl
BETAMETHASONE BENZOATE (200 MG) BETAMETHASONE BENZOATE (200 MG) 22298-29-9 C35H41FO8
TIZANIDINE RELATED COMPOUND B (50 MG) (N-ACETYLTIZANIDINE) TIZANIDINE RELATED COMPOUND B (50 MG) (N-ACETYLTIZANIDINE) 173532-15-5 C11H10ClN5OS
4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL 76014-81-8 C10H15N3O2
YS-035 HCL YS-035 HCL 33978-72-2 C21H29NO4
Tritosulfuron Tritosulfuron 142469-14-5 C13H9F6N5O4S
SULCOFURON-SODIUM MONOHYDRATE SULCOFURON-SODIUM MONOHYDRATE 3567-25-7 C19H11Cl4N2O5S.Na.H2O
TRANSFORMER OIL TRANSFORMER OIL 64742-53-6
PHENYTOIN RELATED COMPOUND B (50 MG) (AL-PHA-((AMINOCARBONYL)AMINO)-ALPHA-PHENYL  BEN-ZENEACETIC ACID) PHENYTOIN RELATED COMPOUND B (50 MG) (AL-PHA-((AMINOCARBONYL)AMINO)-ALPHA-PHENYL BEN-ZENEACETIC ACID) 6802-95-5 C15H14N2O3
METRAFENONE METRAFENONE 220899-03-6 C19H21BrO5
9,11-Didehydroestriol 9,11-Didehydroestriol 246021-20-5 C18H22O3
DESETHYL CHLOROQUINE DESETHYL CHLOROQUINE 1476-52-4 C16H22ClN3
METHYL CHLORODIBROMOACETATE METHYL CHLORODIBROMOACETATE 20428-75-5 C3H3Br2ClO2
BENZO(A)FLUORANTHENE BENZO(A)FLUORANTHENE 203-33-8 C20H12
2-CHLORO-4-NITROBENZENEDIAZONIUM 2-NAPHTHALENESULFONATE 2-CHLORO-4-NITROBENZENEDIAZONIUM 2-NAPHTHALENESULFONATE 6035-19-4 C16H10ClN3O5S
D-PENICILLAMINE DISULFIDE D-PENICILLAMINE DISULFIDE 20902-45-8 C10H20N2O4S2
3-Ketocarbofuranphenol 3-Ketocarbofuranphenol 17781-16-7 C10H10O3
3-Nitro-4-phenoxy-5-sulfaMoylbenzoic Acid 3-Nitro-4-phenoxy-5-sulfaMoylbenzoic Acid 28328-53-2 C13H10N2O7S
DESMETHYL MIRTAZAPINE DESMETHYL MIRTAZAPINE 61337-68-6 C16H17N3
(R,S)-NORCOTININE (R,S)-NORCOTININE 17708-87-1 C9H10N2O
N-NITROSOANATABINE N-NITROSOANATABINE 887407-16-1 C10H11N3O
ALLOPURINOL IMPURITY C ALLOPURINOL IMPURITY C 1346604-13-4 C6H6N6O
ALACHLOR-D13 ALACHLOR-D13 1015856-63-9 C14H7ClD13NO2
CLORAZEPATE DIPOTASSIUM SALT CLORAZEPATE DIPOTASSIUM SALT 57109-90-7 C16H13ClK2N2O4
Loperamide Loperamide 106900-12-3 C29H33ClN2O3
L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- 2410-93-7 C20H21N7O6
TRIETHYLENETETRAMINE DISULFATE DIHYDRATE TRIETHYLENETETRAMINE DISULFATE DIHYDRATE 25291-67-2 C6H22N4O8S2
Orthosulfamuron Orthosulfamuron 213464-77-8 C16H20N6O6S
CIMBUTEROL CIMBUTEROL 54239-39-3 C13H19N3O
BENZO(G,H,I)FLUORANTHENE BENZO(G,H,I)FLUORANTHENE 203-12-3 C18H10
2-(Acetylsulfanyl)ethanesulphonic 2-(Acetylsulfanyl)ethanesulphonic 69536-71-6 C4H8O4S2
rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol 56718-76-4 C12H17ClO3
GLYFOSATE 13C2 15N GLYFOSATE 13C2 15N 285978-24-7 C3H8NO5P
1-[[(2S,3S)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl]-1,2,4-triazole 1-[[(2S,3S)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl]-1,2,4-triazole 133855-98-8 C17H13ClFN3O
ECGONINE METHYL ESTER ECGONINE METHYL ESTER 7143-09-1 C10H17NO3
3-(N-ACETYLAMINO)-5-(N-DECYL-N-METHYLAMINO)BENZYL ALCOHOL 3-(N-ACETYLAMINO)-5-(N-DECYL-N-METHYLAMINO)BENZYL ALCOHOL 103955-90-4 C20H34N2O2
DITRIDECYL PHTHALATE DITRIDECYL PHTHALATE 119-06-2 C34H58O4
METHYL 6-TRANS-OCTADECENOATE METHYL 6-TRANS-OCTADECENOATE 14620-36-1 C19H36O2
5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide monohydrate 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide monohydrate 73360-56-2 C13H8Cl2N2O4.H2O
Albuterol Aldehyde Albuterol Aldehyde 156339-88-7 C13H19NO3
Hydroxy Ipronidazole-d3 Hydroxy Ipronidazole-d3 1156508-86-9 C7H11N3O3
4-phenylbutylphosphonic acid 4-phenylbutylphosphonic acid 46348-61-2 C10H15O3P
17R-Drospirenone 17R-Drospirenone 90457-65-1 C24H30O3
Trandolapril Related Compound D (25 mg) ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate) Trandolapril Related Compound D (25 mg) ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate) 149881-40-3 C24H32N2O4
Benzoic acid, 2-(hexahydro-1-Methyl-1H-azepin-4-yl)hydrazide Benzoic acid, 2-(hexahydro-1-Methyl-1H-azepin-4-yl)hydrazide 110406-94-5 C14H21N3O
METHYLENE CHLORIDE (13C) METHYLENE CHLORIDE (13C) 70110-03-1 CH2Cl2
PENTACHLOROPHENOL ACETATE PENTACHLOROPHENOL ACETATE 1441-02-7 C8H3Cl5O2
ANTIPYRYLAZO III ANTIPYRYLAZO III 14918-39-9 C32H28N8O10S2
LARD OIL LARD OIL 8016-28-2
TILIDINE HYDROCHLORIDE HEMIHYDRATE TILIDINE HYDROCHLORIDE HEMIHYDRATE 27107-79-5 C17H26ClNO3
CARBENDAZIM D3 CARBENDAZIM D3 1255507-88-0 C9H6D3N3O2
BENZO(C)ACRIDINE BENZO(C)ACRIDINE 225-51-4 C17H11N
4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid 4-cyclohexyl-alpha-methylnaphthalene-1-acetic acid 71109-09-6 C19H22O2
2-MONOSTEARIN 2-MONOSTEARIN 621-61-4 C21H42O4
MOLYBDOVANADATE REAGENT MOLYBDOVANADATE REAGENT H3MoO7V
1-AMINO-2,4-IMIDAZOLIDINEDIONE-13C3 1-AMINO-2,4-IMIDAZOLIDINEDIONE-13C3 957509-31-8 C3H5N3O2
eicosapentaenoic acid ethyl ester eicosapentaenoic acid ethyl ester 73310-10-8 C22H34O2
Haloxyfop-P Haloxyfop-P 95977-29-0 C15H11ClF3NO4
BIS(2-ETHYLHEXYL)ISOPHTHALATE BIS(2-ETHYLHEXYL)ISOPHTHALATE 137-89-3 C24H38O4
5-METHYL-N,N-DIMETHYLTRYPTAMINE 5-METHYL-N,N-DIMETHYLTRYPTAMINE 22120-39-4 C13H18N2
BENZO[B]NAPHTHO[2,1-D]FURAN BENZO[B]NAPHTHO[2,1-D]FURAN 239-30-5 C16H10O
5-[4-(tert-Octyl)phenoxy]-3-oxapentane-1-ol 5-[4-(tert-Octyl)phenoxy]-3-oxapentane-1-ol 2315-61-9 C18H30O3
CLEBOPRIDE MALATE CLEBOPRIDE MALATE 57645-91-7 C20H24ClN3O2.C4H6O5
2-NP-AOZ-D4 2-NP-AOZ-D4 1007478-57-0 C10H9N3O4
1,2,3-TRINONADECANOYLGLYCEROL 1,2,3-TRINONADECANOYLGLYCEROL 26536-13-0 C60H116O6
1-(3-Chlorophenyl)-1-hydroxy-2-propanone 1-(3-Chlorophenyl)-1-hydroxy-2-propanone 857233-13-7 C9H9ClO2
6-APB (6-(2-aminopropyl)benzofuran) 6-APB (6-(2-aminopropyl)benzofuran) 286834-84-2 C11H14ClNO
3S, 5S enantioMer of Atorvastatin CalciuM 3S, 5S enantioMer of Atorvastatin CalciuM 1105067-88-6 C33H34CaFN2O5+
SalMeterol Xinafoate Adduct IMpurity SalMeterol Xinafoate Adduct IMpurity 1330076-52-2 C36H43NO6
Telmisartan Related Compound B (15 mg) (4'-[(1,7'-dimethyl-2'-propyl-1H,1'H-2,5'-bibenzo[d]imidazol-1'-yl)methyl]biphenyl-2-carboxylic acid) Telmisartan Related Compound B (15 mg) (4'-[(1,7'-dimethyl-2'-propyl-1H,1'H-2,5'-bibenzo[d]imidazol-1'-yl)methyl]biphenyl-2-carboxylic acid) 1026353-20-7 C33H30N4O2
CIS-12-OCTADECENOIC ACID METHYL ESTER CIS-12-OCTADECENOIC ACID METHYL ESTER 2733-86-0 C19H36O2
CINIDON-ETHYL CINIDON-ETHYL 142891-20-1 C19H17Cl2NO4
ALLOXYDIM-SODIUM ALLOXYDIM-SODIUM 55635-13-7 C17H24NO5.Na
4,4'-DDT D8 4,4'-DDT D8 93952-18-2 C14HCl5D8
QUINONAMID QUINONAMID 27541-88-4 C12H6Cl3NO3
5ALPHA-ANDROSTAN-17BETA-OL-3-ONE-16,16,17-D3 5ALPHA-ANDROSTAN-17BETA-OL-3-ONE-16,16,17-D3 79037-34-6 C19H30O2
NITRITE ION CHROMATOGRAPHY STANDARD NITRITE ION CHROMATOGRAPHY STANDARD NO2-
EPOXIDIZED LINSEED OIL EPOXIDIZED LINSEED OIL 8016-11-3
SODIUM HYDROXIDE MONOHYDRATE SODIUM HYDROXIDE MONOHYDRATE 12200-64-5 H3NaO2
P-CRESOL-D8 P-CRESOL-D8 190780-66-6 C7H8O
HEPTALDEHYDE (DNPH DERIVATIVE) HEPTALDEHYDE (DNPH DERIVATIVE) 2074-05-7 C13H18N4O4
5-ALLYL-5-[1-METHYLBUTYL]-2-THIOBARBITURIC ACID 5-ALLYL-5-[1-METHYLBUTYL]-2-THIOBARBITURIC ACID 77-27-0 C12H18N2O2S
(S S)-ETHYLENEDIAMINE-N N-DISUCCINIC ACI (S S)-ETHYLENEDIAMINE-N N-DISUCCINIC ACI 178949-82-1 C10H17N2NaO8
TERBUTYLAZINE-2-HYDROXY PESTANAL  250 MG TERBUTYLAZINE-2-HYDROXY PESTANAL 250 MG 66753-07-9 C9H17N5O
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) 27244-64-0 C9H11NO5
IRON(II) SULFATE DIHYDRATE IRON(II) SULFATE DIHYDRATE 10028-21-4 FeH4O6S
PEAK E PEAK E 132685-02-0 C24H26N4O4
1-METHYLBENZO(A)ANTHRACENE 1-METHYLBENZO(A)ANTHRACENE 2498-77-3 C19H14
Chlorcyclizine hydrochloride Chlorcyclizine hydrochloride 14362-31-3 C18H22Cl2N2
BROMFENVINPHOS BROMFENVINPHOS 33399-00-7 C12H14BrCl2O4P
1-[4-(2-Hydroxyethyl)phenoxy]-2,3-epoxypropane 1-[4-(2-Hydroxyethyl)phenoxy]-2,3-epoxypropane 63659-17-6 C15H20O3
Almagate Almagate 66827-12-1 CH6AlMgO4(-3)
DifcoTM Skim Milk DifcoTM Skim Milk
3’,4’,5’-Trihydroxy-6,7-dimethoxyflavone 3’,4’,5’-Trihydroxy-6,7-dimethoxyflavone 29536-41-2 C17H14O7
Sinapine Sinapine 18696-26-9 [C16H24NO5]+.
6BETA-HYDROXYTESTOSTERONE 6BETA-HYDROXYTESTOSTERONE 62-99-7 C19H28O3
ALKANE C48 ALKANE C48 7098-26-2 C48H98
3-Methyl-quinoxaline-2-carboxylic Acid 3-Methyl-quinoxaline-2-carboxylic Acid 74003-63-7 C10H8N2O2
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