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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
BENZO(B)CHRYSENE BENZO(B)CHRYSENE 214-17-5 C22H14
MEFLUIDIDE MEFLUIDIDE 53780-34-0 C11H13F3N2O3S
1,3-Dipalmitoyl-2-oleoylGlycerol 1,3-Dipalmitoyl-2-oleoylGlycerol 2190-25-2 C53H100O6
1-METHYL-4-[THIOXANTHEN-9-YLIDENE]PIPERIDINE MALEATE SALT 1-METHYL-4-[THIOXANTHEN-9-YLIDENE]PIPERIDINE MALEATE SALT 13187-06-9 C23H23NO4S
ACETAMINOPHEN-D4 ACETAMINOPHEN-D4 64315-36-2 C8H5D4NO2
KELEVAN KELEVAN 4234-79-1 C17H12Cl10O4
P-IODOCLONIDINE HYDROCHLORIDE P-IODOCLONIDINE HYDROCHLORIDE 108294-53-7 C9H8Cl2IN3
4-Hydroxy-3-mesityl-1-oxaspiro(4.4)non-3-en-2-one 4-Hydroxy-3-mesityl-1-oxaspiro(4.4)non-3-en-2-one 148476-30-6 C17H20O3
4-O-BETA-GALACTOPYRANOSYL-D-MANNOPYRANOSE 4-O-BETA-GALACTOPYRANOSYL-D-MANNOPYRANOSE 50468-56-9 C12H22O11
P-HYDROXYMETHAMPHETAMINE P-HYDROXYMETHAMPHETAMINE 370-14-9 C10H15NO
NODULARIN NODULARIN 118399-22-7 C41H60N8O10
N-Desmethyl Clomipramine Hydrochloride N-Desmethyl Clomipramine Hydrochloride 29854-14-6 C18H22Cl2N2
Desisobutyryl Ciclesonide Desisobutyryl Ciclesonide 161115-59-9 C28H38O6
1-(3-Chlorophenyl)-2-hydroxy-1-propanone 1-(3-Chlorophenyl)-2-hydroxy-1-propanone 152943-33-4 C9H9ClO2
Morphine Sulfate Morphine Sulfate 6211-15-0 C34H50N2O15S
FENFURAM FENFURAM 24691-80-3 C12H11NO2
BUTAMIFOS BUTAMIFOS 36335-67-8 C13H21N2O4PS
Desmethyl Chlorpheniramine Maleate Salt Desmethyl Chlorpheniramine Maleate Salt 22630-25-7 C19H21ClN2O4
LEUCOMALACHITE GREEN D6 LEUCOMALACHITE GREEN D6 1173021-13-0 C23H20D6N2
ALKANE C42 ALKANE C42 7098-20-6 C42H86
MORPHINE-D3 MORPHINE-D3 67293-88-3 C17H19NO3
IODOMETHANE-D2 IODOMETHANE-D2 865-43-0 CHD2I
6-NITROBENZ(A)PYRENE 6-NITROBENZ(A)PYRENE 63041-90-7 C20H11NO2
CARVACROL METHYL ETHER CARVACROL METHYL ETHER 6379-73-3 C11H16O
(N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl)phosphonium bromide (N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl)phosphonium bromide 226409-58-1 Br1C33H39N1O13P1
CAMYLOFINE DIHYDROCHLORIDE CAMYLOFINE DIHYDROCHLORIDE 54-30-8 C19H32N2O2
INDAPAMIDE RELATED COMPOUND A (50 MG) (4-CHLORO-N-(2-METHYL-INDOL-1-YL)-3-SULFAMOYLBEN-ZAMIDE) (AS) INDAPAMIDE RELATED COMPOUND A (50 MG) (4-CHLORO-N-(2-METHYL-INDOL-1-YL)-3-SULFAMOYLBEN-ZAMIDE) (AS) 63968-75-2 C16H14ClN3O3S
DESETHYLENE CIPROFLOXACIN, HYDROCHLORIDE DESETHYLENE CIPROFLOXACIN, HYDROCHLORIDE 528851-31-2 C15H16FN3O3.ClH
PINOXADEN PINOXADEN 243973-20-8 C23H32N2O4
OXOLINIC ACID IMPURITY B OXOLINIC ACID IMPURITY B 16172-03-5 C15H15NO5
exo-Granisetron (Granisetron Impurity F) exo-Granisetron (Granisetron Impurity F) 127472-42-8 C18H24N4O
1-(4-AMINO-3,5-DICHLORO-PHENYL)-2-ISOPROPYLAMINO-ETHANOL(CLENPROPEROL) 1-(4-AMINO-3,5-DICHLORO-PHENYL)-2-ISOPROPYLAMINO-ETHANOL(CLENPROPEROL) 38339-11-6 C11H16Cl2N2O
DEACYLGYMNEMIC ACID DEACYLGYMNEMIC ACID 121686-42-8 C36H58O12
4,4'-DDM 4,4'-DDM 101-76-8 C13H10Cl2
CASANTHRANOL CASANTHRANOL 8024-48-4 C21H22O10
CYFLUFENAMID CYFLUFENAMID 180409-60-3 C20H17F5N2O2
2,2',4,4',5,5'-HEXABROMODIPHENYL ETHER 2,2',4,4',5,5'-HEXABROMODIPHENYL ETHER 68631-49-2 C12H4Br6O
Sulfisozole sodium Sulfisozole sodium 79921-43-0 C9H8N3NaO3S
dacisteine dacisteine 18725-37-6 C7H11NO4S
(±)-2-methyl-1-nitrosoindoline (±)-2-methyl-1-nitrosoindoline 85440-79-5 C9H10N2O
(5alpha)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one (5alpha)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one 508-54-3 C18H19NO4
7,8-Dihydro-14-hydroxy- normorphinone 7,8-Dihydro-14-hydroxy- normorphinone 33522-95-1 C16H17NO4
Alachlor OA, Pestanal Alachlor OA, Pestanal 171262-17-2 C14H19NO4
Desethyl Amiodarone Hydrochloride Desethyl Amiodarone Hydrochloride 96027-74-6 C23H26ClI2NO3
rac N'-Nitrosonornicotine rac N'-Nitrosonornicotine 80508-23-2 C9H11N3O
BROMATE-BROMIDE BROMATE-BROMIDE Br2O3-2
AMIPROFOS METHYL AMIPROFOS METHYL 36001-88-4 C11H17N2O4PS
7-hydroxy-2-methyl-4H-chromen-4-one 7-hydroxy-2-methyl-4H-chromen-4-one 6320-42-9 C10H8O3
Zinc standard Zinc standard Zn
3-Oxo Ropinirole Hydrochloride
3-Oxo Ropinirole Hydrochloride 221264-21-7 C16H23ClN2O2
AceproMazine-d6 Maleate AceproMazine-d6 Maleate 1331655-50-5 C23H26N2O5S
Praziquantel-d11 Praziquantel-d11 1246343-36-1 C19H24N2O2
Des[2-[(2-Hydroxyethyl)aMino]ethyl] Mitoxantrone
(Mitoxantrone IMpurity A) Des[2-[(2-Hydroxyethyl)aMino]ethyl] Mitoxantrone (Mitoxantrone IMpurity A) 89991-52-6 C18H19N3O5
BUTACAINE BUTACAINE 149-16-6 C18H30N2O2
HIDE POWDER HIDE POWDER
ACETOCHLOR D11 ACETOCHLOR D11 1189897-44-6 C14H20ClNO2
(+)-P-MENTH-1-ENE (+)-P-MENTH-1-ENE 1195-31-9 C10H18
CARBAMAZEPINE-D10 CARBAMAZEPINE-D10 132183-78-9 C15H2D10N2O
ETHYLENE OXIDE (1,2-13C2) ETHYLENE OXIDE (1,2-13C2) 84508-46-3 C2H4O
ETHYLHYDROCUPREINE ETHYLHYDROCUPREINE 522-60-1 C21H28N2O2
OXYBUTYNIN IMPURITY A OXYBUTYNIN IMPURITY A 1199574-71-4 C22H35NO3
DIBENZYLPHTHALATE-D4 DIBENZYLPHTHALATE-D4 1015854-62-2 C22H14D4O4
HYDRANAL(R)-COMPOSITE 5 HYDRANAL(R)-COMPOSITE 5
ECGONIN HCL ECGONIN HCL 5796-31-6 C9H16ClNO3
IODOMETHANE-D1 IODOMETHANE-D1 992-96-1 CH2DI
BIS-(4-DIMETHYLAMINOPHENYL)PHENYL-D5-METHANE BIS-(4-DIMETHYLAMINOPHENYL)PHENYL-D5-METHANE 947601-82-3 C23H21D5N2
BENZO[B]NAPHTHO[1,2-D]FURAN BENZO[B]NAPHTHO[1,2-D]FURAN 205-39-0 C16H10O
CARBON TETRACHLORIDE (13C) CARBON TETRACHLORIDE (13C) 32488-50-9 CCl4
Althiazide Althiazide 5588-16-9 C11H14ClN3O4S3
DIBENZO(A,E)FLUORANTHENE DIBENZO(A,E)FLUORANTHENE 5385-75-1 C24H14
5(6)-CARBOXYNAPHTHOFLUORESCEIN 5(6)-CARBOXYNAPHTHOFLUORESCEIN 128724-35-6 C29H16O7
M-6-G TRIFLUOROACETATE-HYDRATE M-6-G TRIFLUOROACETATE-HYDRATE 20290-10-2 C23H27NO9
3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)propyl(methyl)ammonium chloride 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)propyl(methyl)ammonium chloride 438-59-5 C19H20ClN
Dimetridazol-D3, Vetranal Dimetridazol-D3, Vetranal 64678-69-9 C5H7N3O2
ALKANE C54 ALKANE C54 5856-66-6 C54H110
METHYLDYMRON METHYLDYMRON 42609-73-4 C17H20N2O
Furilazole Furilazole 121776-33-8 C11H13Cl2NO3
Proquinazid Proquinazid 189278-12-4 C14H17IN2O2
1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine 1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine 97928-18-2 C19H29NO2
3-hydroxy-1-methyl-5-pyridin-3-yl-pyrrolidin-2-one 3-hydroxy-1-methyl-5-pyridin-3-yl-pyrrolidin-2-one 34834-67-8 C10H12N2O2
butyl 2-[4-(4-cyano-2-fluoro-phenoxy)phenoxy]propanoate butyl 2-[4-(4-cyano-2-fluoro-phenoxy)phenoxy]propanoate 122008-78-0 C16H12FNO4
DIAZEPAM-D5 DIAZEPAM-D5 65854-76-4 C16H8ClD5N2O
benazepril hydrochloride benazepril hydrochloride 215447-89-5 C24H28N2O5HCl
L-Nateglinide L-Nateglinide 105816-05-5 C19H27NO3
BETA-ZEARALANOL BETA-ZEARALANOL 42422-68-4 C18H26O5
1-Galloyl-glucose 1-Galloyl-glucose 13405-60-2 C13H16O10
2,2',3,4,4',5'-HEXABDE 2,2',3,4,4',5'-HEXABDE 182677-30-1 C12H4Br6O
2,2',3,4',5,6-HEXACHLOROBIPHENYL 2,2',3,4',5,6-HEXACHLOROBIPHENYL 68194-13-8 C12H4Cl6
SULOCTIDIL SULOCTIDIL 54767-75-8 C20H35NOS
CHLORODIBROMOACETIC ACID CHLORODIBROMOACETIC ACID 5278-95-5 C2HBr2ClO2
1-(4-Fluorophenyl-d4)-4-(4-(2-pyridinyl)-1-piperazinyl)-1-butanone,  4'-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone-d4 1-(4-Fluorophenyl-d4)-4-(4-(2-pyridinyl)-1-piperazinyl)-1-butanone, 4'-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone-d4 1173021-72-1 C19H18D4FN3O
THIOCHROME THIOCHROME 92-35-3 C12H14N4OS
cis-Tranylcypromine hydrochloride cis-Tranylcypromine hydrochloride 54779-58-7 C9H12ClN
SAXITOXIN SAXITOXIN 35523-89-8 C10H17N7O4
(1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride 172015-79-1 C11H12ClN5O.ClH
Atorvastatin Related Compound C Atorvastatin Related Compound C 693793-53-2 C33H36CaF2N2O5
[2-(3-pyridinyl)ethylidene-1,1]bis(phosphonic acid) [2-(3-pyridinyl)ethylidene-1,1]bis(phosphonic acid) 75755-10-1 C7H11NO6P2
2,2'-Binaphthalene-6,6'-dicarboxylic Acid 2,2'-Binaphthalene-6,6'-dicarboxylic Acid 932033-58-4 C22H14O4
Doxercalciferol-D3 Doxercalciferol-D3 1217448-46-8 C28H44O
LANTHANUM NITRATE LANTHANUM NITRATE 10099-59-9 HLaNO3
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