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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
apovincamine apovincamine 4880-92-6 C21H24N2O2
SPIROMESIFEN SPIROMESIFEN 283594-90-1 C23H30O4
BETA-ELEMENE BETA-ELEMENE 515-13-9 C15H24
p-methoxy-N,alpha-dimethylphenethylamine hydrochloride p-methoxy-N,alpha-dimethylphenethylamine hydrochloride 3398-68-3 C11H18ClNO
Diethylhexyl Butamido Triazone Diethylhexyl Butamido Triazone 154702-15-5 C44H59N7O5
RAC CARPROFEN-D3 RAC CARPROFEN-D3 1173019-42-5 C15H11ClNO2
2,2',4,5'-TETRABROMODIPHENYL ETHER 2,2',4,5'-TETRABROMODIPHENYL ETHER 243982-82-3 C12H6Br4O
2,3,3-TRIMETHYLPENTANE 2,3,3-TRIMETHYLPENTANE 560-21-4 C8H18
17BETA-ESTRADIOL-2,4,16,16,17-D5 17BETA-ESTRADIOL-2,4,16,16,17-D5 221093-45-4 C18H19D5O2
NORDIAZEPAM-D5 NORDIAZEPAM-D5 65891-80-7 C15H11ClN2O
2,3,3',4,4',5,5',6-OCTABROMODIPHENYL ETHER 2,3,3',4,4',5,5',6-OCTABROMODIPHENYL ETHER 446255-56-7 C12H2Br8O
FLUXOFENIM FLUXOFENIM 88485-37-4 C12H11ClF3NO3
TENUAZONIC ACID COPPER FROM ALTERNARIA A TENUAZONIC ACID COPPER FROM ALTERNARIA A 610-88-8 C10H15NO3
RAC 9-HYDROXYRISPERIDONE-D4 RAC 9-HYDROXYRISPERIDONE-D4 1020719-55-4 C23H27FN4O3
FATTY ACID KIT FATTY ACID KIT CnH2nO2
AZAPEROL AZAPEROL 2804-05-9 C19H24FN3O
DOXEPIN-D3 HCL (N-METHYL-D3) DOXEPIN-D3 HCL (N-METHYL-D3) 347840-07-7 C19H19ClD3NO
PRIMVERIN PRIMVERIN 154-60-9 C20H28O13
Bisphenol A Bis(2,3-dihydroxypropyl) Ether Bisphenol A Bis(2,3-dihydroxypropyl) Ether 5581-32-8 C21H28O6
TECLOFTALAM METABOLITE TECLOFTALAM METABOLITE 26491-30-5 C14H3Cl6NO2
2,4-DICHLOROPHENOL (RING-D3) 2,4-DICHLOROPHENOL (RING-D3) 93951-74-7 C6H4Cl2O
ALPHA-HYDROXYTRIAZOLAM ALPHA-HYDROXYTRIAZOLAM 37115-45-0 C17H12Cl2N4O
Dehydronitrendipine Dehydronitrendipine 89267-41-4 C18H18N2O6
Ipronidazole Ipronidazole 14885-29-1 C7H11N3O2
1,5-DIMETHYL-4-NICOTINAMIDO-2-PHENYL-3-PYRAZOLONE 1,5-DIMETHYL-4-NICOTINAMIDO-2-PHENYL-3-PYRAZOLONE 2139-47-1 C17H16N4O2
3'-DEOXYTHYMIDINE-5'-O-TRIPHOSPHATE/2',3'-DIDEOXYTHYMIDINE-5'-O-TRIPHOSPHATE SODIUM SALT 3'-DEOXYTHYMIDINE-5'-O-TRIPHOSPHATE/2',3'-DIDEOXYTHYMIDINE-5'-O-TRIPHOSPHATE SODIUM SALT 128524-26-5 C10H16N2O13P3.Na
Erythromycin A Enol Ether Erythromycin A Enol Ether 33396-29-1 C37H65NO12
Coenzyme Coenzyme 45127-11-5 C4H10O6S4
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride 1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride 850352-11-3 C19H24ClNO
Atorvastatin Related Compound A Atorvastatin Related Compound A 433289-83-9 C33H35CaN2O5+
(3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid (3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid 89913-60-0 C32H50O4
Clenproperol Clenproperol 1173021-09-4 C11H16Cl2N2O
RISPERIDONE-D4 RISPERIDONE-D4 1020719-76-9 C23H23D4FN4O2
4-DesMethyl-3-Methyl Celecoxib 4-DesMethyl-3-Methyl Celecoxib 170570-01-1 C17H14F3N3O2S
Fluconazole-D4 Fluconazole-D4 1124197-58-5 C13H8D4F2N6O
HALOPERIDOL-D4 HALOPERIDOL-D4 136765-35-0 C21H19ClD4FNO2
PYRIFTALID PYRIFTALID 135186-78-6 C15H14N2O4S
4,4'-METHOXYCHLOR OLEFIN 4,4'-METHOXYCHLOR OLEFIN 2132-70-9 C16H14Cl2O2
TRIMETHYLCOLCHICINIC ACID TRIMETHYLCOLCHICINIC ACID 3482-37-9 C19H21NO5
DIPERODON HYDROCHLORIDE DIPERODON HYDROCHLORIDE 537-12-2 C22H28ClN3O4
6-O-METHYLCODEINE 6-O-METHYLCODEINE 2859-16-7 C19H23NO3
SIMAZINE-2-HYDROXY SIMAZINE-2-HYDROXY 2599-11-3 C7H13N5O
(+)-BETA-PINENE (+)-BETA-PINENE 19902-08-0 C10H16
CHLORFENPROP-METHYL CHLORFENPROP-METHYL 14437-17-3 C10H10Cl2O2
OXAZEPAM-D5 OXAZEPAM-D5 65854-78-6 C15H11ClN2O2
DIMOXYSTROBIN  PESTANAL DIMOXYSTROBIN PESTANAL 149961-52-4 C19H22N2O3
Aroclor 1242 Aroclor 1242 53469-21-9 C12H6Cl4
Prednisolone tebutate Prednisolone tebutate 7681-14-3 C27H38O6
MONOSULTAP MONOSULTAP 29547-00-0 C5H12NO6S4.Na
DEMETON O DEMETON O 298-03-3 C8H19O3PS2
2,2',3,4,4',5,6-HEPTABROMODIPHENYL ETHER 2,2',3,4,4',5,6-HEPTABROMODIPHENYL ETHER 189084-67-1 C12H3Br7O
TOPRAMEZONE TOPRAMEZONE 210631-68-8 C16H17N3O5S
7-HYDROXY QUETIAPINE 7-HYDROXY QUETIAPINE 139079-39-3 C21H25N3O3S
ACETOPHENAZINE MALEATE (200 MG) ACETOPHENAZINE MALEATE (200 MG) 5714-00-1 C53H64N6O11S2
2-Chloro-6-[(4,6-dimethoxy-2-pyrimidinyl)thio]benzoic acid 2-Chloro-6-[(4,6-dimethoxy-2-pyrimidinyl)thio]benzoic acid 123342-93-8 C13H11ClN2O4S
Melamine-15N3 Melamine-15N3 287476-11-3 C3H6N315N3
2-METHYLQUINOLINE PHOSPHATE SALT 2-METHYLQUINOLINE PHOSPHATE SALT 118896-93-8 C10H12NO4P
TERBUMETON-DESETHYL TERBUMETON-DESETHYL 30125-64-5 C8H15N5O
BACOPASIDE X BACOPASIDE X 94443-88-6 C46H74O17
(-)-11-NOR-9-CARBOXY-DELTA9-THC (-)-11-NOR-9-CARBOXY-DELTA9-THC 56354-06-4 C21H28O4
N-De(4-sulfonaMidophenyl)-N'-(4-sulfonaMidophenyl) Celecoxib N-De(4-sulfonaMidophenyl)-N'-(4-sulfonaMidophenyl) Celecoxib 331943-04-5 C17H14F3N3O2S
5-APB (hydrochloride) 5-APB (hydrochloride) 286834-80-8 C11H14ClNO
5-[2-Ethoxy-5-[(4-Methyl-4-oxido-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-(2-Methylpropyl)-7H-pyrazolo[4,3-d]pyriMidin-7-one 5-[2-Ethoxy-5-[(4-Methyl-4-oxido-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-(2-Methylpropyl)-7H-pyrazolo[4,3-d]pyriMidin-7-one 1391053-95-4 C23H32N6O4S
ETHYLENE-D4 OXIDE ETHYLENE-D4 OXIDE 6552-57-4 C2D4O
N-[[(HEXAHYDROCYCLOPENTA [C]PYRROL-2(1H)-YL)AMINO]CARBONYL]-2-METHYL BENZENESULFONAMIDE N-[[(HEXAHYDROCYCLOPENTA [C]PYRROL-2(1H)-YL)AMINO]CARBONYL]-2-METHYL BENZENESULFONAMIDE 1076198-18-9 C15H21N3O3S
PHENCYCLIDINE PHENCYCLIDINE 77-10-1 C17H25N
1,7-HEXADECADIENE 1,7-HEXADECADIENE 125110-62-5 C16H30
MELOXICAM-D3 MELOXICAM-D3 942047-63-4 C14H13N3O4S2
ETANIDAZOLE ETANIDAZOLE 22668-01-5 C7H10N4O4
DICHLORPROP-METHYL ESTER DICHLORPROP-METHYL ESTER 57153-17-0 C10H10Cl2O3
ETACONAZOLE ETACONAZOLE 60207-93-4 C14H15Cl2N3O2
ARSENOBETAINE ARSENOBETAINE 64436-13-1 C5H11AsO2
THIAZAFLURON THIAZAFLURON 25366-23-8 C6H7F3N4OS
1-PHENYL-D5-AZO-2-NAPHTHOL 1-PHENYL-D5-AZO-2-NAPHTHOL 752211-63-5 C16H7N2OD5
CANOLA OIL CANOLA OIL 120962-03-0
HALOPERIDOL RELATED COMPOUND A (15 MG) (4,4'-BIS[(4-P-CHLOROPHENYL)-4-HYDROXY-PIPERIDINO]-BU-TYROPHENONE) HALOPERIDOL RELATED COMPOUND A (15 MG) (4,4'-BIS[(4-P-CHLOROPHENYL)-4-HYDROXY-PIPERIDINO]-BU-TYROPHENONE) 67987-08-0 C32H36Cl2N2O3
	NALORPHINE HYDROCHLORIDE NALORPHINE HYDROCHLORIDE 57-29-4 C19H21NO3.ClH
5-Amino-2,4,6-triiodo-N-methylisophthalamic Acid 5-Amino-2,4,6-triiodo-N-methylisophthalamic Acid 2280-89-9 C9H7I3N2O3
CIS-MEVINPHOS PESTANAL  50 MG CIS-MEVINPHOS PESTANAL 50 MG 298-01-1 C7H13O6P
FUSARENON X FUSARENON X 23255-69-8 C17H22O8
2-NP-AMOZ-D5 2-NP-AMOZ-D5 1173097-59-0 C15H18N4O5
AMITRIPTYLINE-D3 HCL (N-METHYL-D3) AMITRIPTYLINE-D3 HCL (N-METHYL-D3) 342611-00-1 C20H24ClN
OXITROPIUM BROMIDE OXITROPIUM BROMIDE 30286-75-0 C19H26BrNO4
N-(1-METHYLETHYL)-N-(PHENYL)OXALAMIC ACID N-(1-METHYLETHYL)-N-(PHENYL)OXALAMIC ACID 70628-36-3 C11H13NO3
4-Benzyl Albuterol 4-Benzyl Albuterol 56796-66-8 C20H27NO3
cephaeline hydrochloride cephaeline hydrochloride 5853-29-2 C28H39ClN2O4
2,2',3,4',4-PENTABDE 2,2',3,4',4-PENTABDE 182346-21-0 C12H5Br5O
5-hydroxymebendazole 5-hydroxymebendazole 60254-95-7 C16H15N3O3
RABENZAZOLE RABENZAZOLE 40341-04-6 C12H12N4
2,2',3,3',4,4',5,5',6-nonabromodiphenylether 2,2',3,3',4,4',5,5',6-nonabromodiphenylether 63387-28-0 C12HBr9O
7-AMINO-3-[(Z)-PROP-1-ENYL]-3-CEPHEM-4-CARBOXYLIC ACID 7-AMINO-3-[(Z)-PROP-1-ENYL]-3-CEPHEM-4-CARBOXYLIC ACID 106447-44-3 C10H12N2O3S
2,6-Diisopropyl-1,4-benzoquinone 2,6-Diisopropyl-1,4-benzoquinone 1988-11-0 C12H16O2
Diltiazem EP Impurity B Diltiazem EP Impurity B 87447-47-0 C18H17NO4S
PYRANOCOUMARIN PYRANOCOUMARIN 518-20-7 C20H18O4
RICININE RICININE 524-40-3 C8H8N2O2
Repaglinide EP Impurity E Repaglinide EP Impurity E 147852-26-4 C27H36N2O4
TMIO TMIO 136440-22-7 C6H10N2O
DIMETHYL-D6 PHTHALATE DIMETHYL-D6 PHTHALATE 85448-30-2 C10H10O4
HydroxyMethyl Clenbuterol HydroxyMethyl Clenbuterol 38339-18-3 C12H18Cl2N2O2
Gemfibrozil Related Compound A ,(E,Z)-2,2-dimethyl-5-[2,5-dimethyl-4-(propene-1-yl)phenoxy]valeric acid Gemfibrozil Related Compound A ,(E,Z)-2,2-dimethyl-5-[2,5-dimethyl-4-(propene-1-yl)phenoxy]valeric acid 500904-61-0 C18H26O3
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