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VAR10300 dihydrochloride

VAR10300 dihydrochloride ??? ???
?? ??:
64821-19-8
???:
VAR10300 dihydrochloride
???(??):
M30 dihydrochloride;M-30 dihydrochloride;VAR10300 dihydrochloride;MAO-IN-M30 dihydrochloride;5-[[Methyl(2-propyn-1-yl)amino]methyl]-8-quinolinol Dihydrochloride;5-((Methyl(prop-2-yn-1-yl)amino)methyl)quinolin-8-ol dihydrochloride;5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride;N-(8-Hydroxy-5-quinolylmethyl)-N-methyl-2-propynylamine dihydrochloride
CBNumber:
CB22750653
???:
C14H15ClN2O
??? ??:
262.74
MOL ??:
64821-19-8.mol
MSDS ??:
SDS

VAR10300 dihydrochloride ??

?? ??
2-8°C
???
DMSO, ?? ? ???: ≥21mg/mL
??? ??
??
??
??-???
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?? 100mM?? ???
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22-41
????? 26-39
WGK ?? 3
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 1 ?? GHS hazard pictograms P280, P305+P351+P338, P310
??????:
P280 ????/???/???/?????? ?????.

VAR10300 dihydrochloride C??? ??, ??, ??

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M 30 Dihydrochloride is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA (Cat. No. 2547) induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson''s disease model.

VAR10300 dihydrochloride ?? ?? ? ???

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VAR10300 dihydrochloride ?? ??

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