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5-Brom-2'-desoxycytidin

5-Bromo-2'-deoxycytidine Struktur
1022-79-3
CAS-Nr.
1022-79-3
Bezeichnung:
5-Brom-2'-desoxycytidin
Englisch Name:
5-Bromo-2'-deoxycytidine
Synonyma:
5-BR-DC;Aids072378;5-Br-2'-dC;Aids-072378;5-Bromo-dcrd;Bromodeoxycytidine;5-BROMODEOXYCYTIDINE;5-Br-2'-deoxycytidine;2'-DEOXY-5-BROMOCYTIDINE;5-bromo-2’-deoxy-cytidin
CBNumber:
CB8261438
Summenformel:
C9H12BrN3O4
Molgewicht:
306.11
MOL-Datei:
1022-79-3.mol

5-Brom-2'-desoxycytidin Eigenschaften

Siedepunkt:
510.8±60.0 °C(Predicted)
Dichte
2.12±0.1 g/cm3(Predicted)
RTECS-Nr.
HA3705000
storage temp. 
Store at 0°C
pka
14.03±0.60(Predicted)
Aggregatzustand
Powder
Farbe
White to Pale Yellow
CAS Datenbank
1022-79-3(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 40
S-S?tze: 22-36
HS Code  29389090
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

5-Brom-2'-desoxycytidin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

5-Bromo-2'-deoxycytidine (BrdC) is a brominated derivative of the deoxyribonucleoside 2’-deoxycytidine. It induces DNA cross-linking and the formation of DNA strand breaks when incorporated into a DNA fragment in place of cytosine and exposed to UVB damage. BrdC inhibits cytopathogenicity induced by herpes simplex virus 1 (HSV-1) and HSV-2 in infected primary rabbit kidney (PRK) cells (MICs = 0.2-0.3 μg/ml). It decreases the survival of U-1 melanoma cells and AG1522 non-cancerous cells and induces sensitization of both to radiation. BrdC also sensitizes tumors to radiation and reduces tumor volume in a mouse model of glioma using RT-2 cells infused with an adenovirus expressing HSV thymidine kinase (ADV-TK) after implantation. In vivo, BrdC is converted to 5-bromo-2'-deoxyuridine (BrdU) and has been used to label cardiac progenitor cells (CPCs) in a rat model of myocardial infarction.

5-Brom-2'-desoxycytidin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2'-Desoxycytidin 5-HYDROXY-2'-DEOXYCYTIDINE 2'-Desoxycytidinhydrochlorid

Downstream Produkte

5-Brom-2'-desoxycytidin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 140)Lieferanten
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1022-79-3(5-Brom-2'-desoxycytidin)Verwandte Suche:

  • 5-bromo-2’-deoxy-cytidin
  • 2'-DEOXY-5-BROMOCYTIDINE
  • 5-BR-DC
  • 5-BROMO-2'-DEOXYCYTIDINE
  • 5-BROMO-2'-DEOXYCYTIDINE MONOHYDRATE
  • 5-BROMODEOXYCYTIDINE
  • 5-Bromo-2'-deoxy-D-cytidine
  • 5-BROMO-2''-DEOXYCYTIDINE(5-BRDC)
  • Bromodeoxycytidine
  • 5-BROMO-2''-DEOXYCYTIDINE crystalline
  • 5-BROMO-2''-DEOXYCYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
  • 4-Amino-5-bromo-1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 4-Amino-1-(2-deoxy-β-D-ribofuranosyl)-5-bromopyrimidin-2(1H)-one
  • 4-Amino-5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxy-methyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)
  • 5-Bromo-dcrd
  • Aids072378
  • Aids-072378
  • 5-Bromo-2'-deoxycytidine ,98%
  • 4-aMino-5-broMo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2-dihydropyriMidin-2-one
  • 4-AMino-5-broMo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-2(1H)-one
  • 4-Amino-5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxy-methyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-on
  • 5-Br-2'-deoxycytidine
  • 5-Br-2'-dC
  • Cytidine, 5-bromo-2'-deoxy-
  • 5-Bromo-2'-deoxycytidine USP/EP/BP
  • 4-amino-5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 5-Bromo-2'-deoxycytidine
  • 5-Bromo-2''-deoxycytidine
  • 1022-79-3
  • C9H12BrN3O4
  • Nucleotides and Nucleic Acids
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