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(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Struktur
132861-87-1
CAS-Nr.
132861-87-1
Englisch Name:
(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
Synonyma:
PD 81,723;4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine;(2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone;(3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone;(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE;Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-;(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone;(2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone
CBNumber:
CB2484082
Summenformel:
C14H12F3NOS
Molgewicht:
299.31
MOL-Datei:
132861-87-1.mol

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Eigenschaften

Schmelzpunkt:
100-104 °C(Solv: ligroine (8032-32-4))
Siedepunkt:
411.7±45.0 °C(Predicted)
Dichte
1.328±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
L?slichkeit
DMSO: ~13 mg/mL
Aggregatzustand
solid
pka
-1.36±0.13(Predicted)
Farbe
yellow

Sicherheit

WGK Germany  3

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

PD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs.

Biologische Aktivit?t

Allosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo .

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 39)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Aikon International Limited 025-58859352 18068836627
 sales01@aikonchem.com China 15084 58
BOC Sciences --
 info@bocsci.com USA 0 65
Energy Chemical 021-58432009 400-005-6266
 marketing1@energy-chemical.com China 44807 58
Shanghai Universal Biotech Co.,Ltd 13774214275
 zhouzz@univ-bio.com China 24996 58
  • (2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone
  • (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
  • PD 81,723
  • (2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone
  • (3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone
  • 4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine
  • Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-
  • (2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone
  • 132861-87-1
  • C14H12F3NOS
  • Adenosine receptor
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