午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
59944-76-2

THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID synthesis

4synthesis methods
-

Yield:59944-76-2 85%

Reaction Conditions:

with hydrogenchloride;sodium hydroxide in methanol;water;

Steps:

12.v N-(1-azabicyclo[2.2.1]hept-3-yl)-thieno[2,3-b]pyridine-2-carboxamide

C101 (0.700 g, 3.63 mmol) is dissolved in MeOH (15 mL) and 3 mL H2O. 2N NaOH (1.82 mL, 3.63 mmol) is added drop-wise, and the reaction is stirred at rt for 24 h. The reaction is concentrated in vacuo, and H2O (40 mL) is added to dissolve the residue. The resulting solution is acidified to pH 4 using concentrated HCl, and the precipitate is isolated by filtration, yielding thieno[2,3-b]pyridine-2-carboxylic acid (C102) as a white powder (85% yield). MS (EI) for C8H5NO2S, M/z: 179 (M)+.

References:

US2003/153595,2003,A1

THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID Related Search: