4-(TRIFLUOROACETYLAMINO)-1-BUTANOL synthesis
- Product Name:4-(TRIFLUOROACETYLAMINO)-1-BUTANOL
- CAS Number:128238-43-7
- Molecular formula:C6H10F3NO2
- Molecular Weight:185.14
13325-10-5
315 suppliers
$10.00/1g
383-63-1
486 suppliers
$10.00/25g
128238-43-7
13 suppliers
$97.09/1ml
Yield:128238-43-7 100%
Reaction Conditions:
in ethanol at 20;
Steps:
(1) 4-trifluoroacetamidobutanol (Compound 11)
(1)
4-trifluoroacetamidobutanol (Compound 11)
A solution (100 ml) of 4-aminobutanol (2.50 g, 28.05 mmol) and trifluoroacetic acid ethyl ester (19.92 g, 140.26 mmol) in ethanol was stirred at room temperature overnight.
The reaction mixture was concentrated under reduced pressure to give 4-trifluoroacetamidobutanol (11) (5.44 g, q.) as a colorless syrup.
References:
US9404108,2016,B2 Location in patent:Page/Page column 30; 34
13325-10-5
315 suppliers
$10.00/1g
407-25-0
453 suppliers
$9.00/1g
128238-43-7
13 suppliers
$97.09/1ml
13325-10-5
315 suppliers
$10.00/1g
431-47-0
290 suppliers
$10.00/5g
128238-43-7
13 suppliers
$97.09/1ml