Tranilast
|
- $5 - $1732.5
- Product name: Tranilast
- CAS: 53902-12-8
- MF: C18H17NO5
- MW: 327.33
- EINECS:
- MDL Number:MFCD00864787
- Synonyms:2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)-benzoicaci ;n-(3,4-dimethoxycinnamoyl)-anthranilicaci ;n-5’ ;rizaben ;SB-252218;N-(3',4'-DIMETHOXYCINNAMOYL)ANTHRANILIC ACID;2-[[3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]AMINO] BENZOIC ACID;TRANILAST
42 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemcia Scientific
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 5MG
- 10mg
- 50mg
- 100mg
- 500MG
- 1g
- 250mg
- 50
- 5g
- 10g
- 25g
- ManufacturerAK Scientific
- Product numberJ98401
- Product descriptionTranilast
- Packaging5g
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ98401
- Product descriptionTranilast
- Packaging10g
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA675778
- Product description2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+%
- Packaging50mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA675778
- Product description2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+%
- Packaging100mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA675778
- Product description2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+%
- Packaging250mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA675778
- Product description2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+%
- Packaging1g
- Price$12
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA675778
- Product description2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+%
- Packaging5g
- Price$33
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA675778
- Product description2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+%
- Packaging25g
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004086
- Product descriptionRIZABEN 95.00%
- Packaging5MG
- Price$502
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004086
- Product descriptionRIZABEN 95.00%
- Packaging50MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004086
- Product descriptionRIZABEN 95.00%
- Packaging500MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5375
- Product descriptionTranilast
- Packaging100mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2812
- Product descriptionTranilast
- Packaging100mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2812
- Product descriptionTranilast
- Packaging1g
- Price$275
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180735
- Product descriptionTranilast (SB 252218) >99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180735
- Product descriptionTranilast (SB 252218) >99%
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J98401 | Tranilast | 5g | $260 | 2021-12-16 | Buy |
| AK Scientific | J98401 | Tranilast | 10g | $480 | 2021-12-16 | Buy |
| Ambeed | A675778 | 2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+% | 50mg | $5 | 2021-12-16 | Buy |
| Ambeed | A675778 | 2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+% | 100mg | $6 | 2021-12-16 | Buy |
| Ambeed | A675778 | 2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+% | 250mg | $8 | 2021-12-16 | Buy |
| Ambeed | A675778 | 2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+% | 1g | $12 | 2021-12-16 | Buy |
| Ambeed | A675778 | 2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+% | 5g | $33 | 2021-12-16 | Buy |
| Ambeed | A675778 | 2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoicacid 99+% | 25g | $133 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004086 | RIZABEN 95.00% | 5MG | $502 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004086 | RIZABEN 95.00% | 50MG | $721.88 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004086 | RIZABEN 95.00% | 500MG | $1732.5 | 2021-12-16 | Buy |
| ApexBio Technology | A5375 | Tranilast | 100mg | $100 | 2021-12-16 | Buy |
| AvaChem | 2812 | Tranilast | 100mg | $90 | 2021-12-16 | Buy |
| AvaChem | 2812 | Tranilast | 1g | $275 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180735 | Tranilast (SB 252218) >99% | 100mg | $510 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180735 | Tranilast (SB 252218) >99% | 250mg | $765 | 2021-12-16 | Buy |
Properties
Melting point :166.2-168.2 °C (lit.)
Boiling point :465.23°C (rough estimate)
Density :1.3185 (rough estimate)
refractive index :1.5100 (estimate)
storage temp. :2-8°C
solubility :DMSO: 18 mg/mL
form :powder
pka :3.47±0.36(Predicted)
color :white to beige
Merck :14,9570
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :NZHGWWWHIYHZNX-CSKARUKUSA-N
CAS DataBase Reference :53902-12-8(CAS DataBase Reference)
Boiling point :465.23°C (rough estimate)
Density :1.3185 (rough estimate)
refractive index :1.5100 (estimate)
storage temp. :2-8°C
solubility :DMSO: 18 mg/mL
form :powder
pka :3.47±0.36(Predicted)
color :white to beige
Merck :14,9570
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :NZHGWWWHIYHZNX-CSKARUKUSA-N
CAS DataBase Reference :53902-12-8(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Tranilast is a compound that exhibits anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells. Tranilast suppresses production of prostaglandin D2 (IC50 = 0.1 mM), prostaglandin E2 (IC50 = ~1-20 μM), thromboxane B2 (IC50 = ~10-50 μM), TGF-β1 (IC50 = ~100-200 μM), and interleukin-8 (IC50 = ~100 μM) in in vitro models as well as attenuates of the proinflammatory activity of human monocytes. While originally marketed as an antiallergenic drug, the efficacy of tranilast in preventing restenosis after percutaneous coronary intervention has been tested in a large-scale clinical trial. Additionally, tranilast inhibits VEGF-induced angiogenetic activities (i.e., proliferation, migration and tube formation of vascular endothelial cells) with IC50 values of 22, 18 and 193 μM, which may prove therapeutic for various retinal diseases.Related product price
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