Acetone
Product identifier
- Product name: Acetone
- CBnumber: CB3130928
- CAS: 67-64-1
- EINECS Number: 200-662-2
- Synonyms: acetone,propan-2-one
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Acetone
- Synonyms: acetone,propan-2-one
- CAS: 67-64-1
- EC number: 200-662-2
- MF: C3H6O
- MW: 58.08
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.
Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb? ). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and
sources of ignition.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: butyl-rubber
Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Butoject? (KCL 898)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Latex gloves
Minimum layer thickness: 0,6 mm Break through time: 10 min
Material tested:Lapren? (KCL 706 / Aldrich Z677558, Size M)
Flame retardant antistatic protective clothing.
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type AX
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- Appearancecolorless clear, liquid
- Odourpungent, weakly aromatic
- Odour Threshold0,1 ppm
- pH5 - 6 at 395 g/l at 20 °C
- Melting point/freezing pointMelting point/range: -94 °C - lit. 56 °C at 1.013 hPa - lit.
- Initial boiling point and boiling range 56 °C at 1.013 hPa - lit.
- Flash point-17,0 °C - closed cup
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 13 %(V) Lower explosion limit: 2 %(V)
- Vapour pressure 245,3 hPa at 20,0 °C
- Vapour density 2 (vs air)
- Relative density0,791 g/cm3 at 25 °C
- Water solubilitysoluble, in all proportions
- Partition coefficient: n-octanol/waterNo data available
- Autoignition temperature 465,0 °C
- Decomposition temperature Distillable in an undecomposed state at normal pressure.
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant2.27 at 14.9 °C, 3.03 at 25 °C, 7.69 at 35.1 °C, 11.76 at 44.9 °C (Betterton, 1991)
Other safety information
Conductivity 0,01 μS/cm at 20 °C Surface tension 23,2 mN/m at 20,0 °C
Reactivity
Vapors may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Risk of ignition or formation of inflammable gases or vapours with: chromosulfuric acid
chromyl chloride ethanolamine
Fluorine
Strong oxidizing agents strong reducing agents Nitric acid chromium(VI) oxide Risk of explosion with: nonmetallic oxyhalides
halogen-halogen compounds Chloroform
nitrating acid nitrosyl compounds hydrogen peroxide halogen oxides
organic nitro compounds peroxi compounds Exothermic reaction with: Bromine
Alkali metals alkali hydroxides
Halogenated hydrocarbon Sulfur dichloride phosphorous oxichloride
Conditions to avoid
Warming.
Incompatible materials
rubber, various plastics
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityRemarks:
(ECHA)
LC50 Inhalation - Rat - 4 h - 76 mg/l Remarks:
Unconsciousness Drowsiness Dizziness (External MSDS)
LD50 Dermal - Rabbit - 20.000 mg/kg Remarks:
(IUCLID)
Result: Mild skin irritation - 24 h (Draize Test)
Remarks:
(RTECS)
Result: Eye irritation - 24 h (Draize Test)
Remarks:
(RTECS)
(ECHA)
Chronic exposure may cause dermatitis.
Result: negative Ames test
Salmonella typhimurium Result: negative
In vitro mammalian cell gene mutation test Mouse lymphoma test
Result: negative
Toxicity
6.210 mg/l - 96 h
(OECD Test Guideline 203)
static test LC50 - Daphnia pulex (Water flea) - 8.800 mg/l - 48 h Remarks: (ECHA)
(DIN 38412)
Remarks: (maximum permissible toxic concentration) (IUCLID)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 91 % - Readily biodegradable. (OECD Test Guideline 301B)
Biochemical Oxygen Demand (BOD)
Chemical Oxygen Demand (COD)
Theoretical oxygen demand
1.850 mg/g Remarks: (IUCLID)
2.070 mg/g Remarks: (IUCLID)
2.200 mg/g Remarks: (Lit.)
Bioaccumulative potential
Does not bioaccumulate.
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Additional ecological No data available
information
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
IncompatibilitiesAcetone reacts violently with oxidizing agents, chlorinated solvents, and alkali mixtures. It reacts vigorously with sulfur dichloride, potassium t-butoxide, and hexachloromelamine. Acetone should not be used as a solvent for iodine, as it forms a volatile compound that is extremely irritating to the eyes.
Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Incineration.
UN number
UN proper shipping name
Transport hazard class(es)
ADR/RID: 3 IMDG: 3 IATA: 3
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.