Pro-Tan®
(50% Tannalbin-Stable Tannins & Igy)
-The milestone of the Innovative livestock feed additives
The chemical composition of Pro-Tan® : 50% Tannalbin-Stable Tannins & Igy
Tannalbin is a typical antidiarrheal medicine embodied into:
1) many national Pharmacopoeias including Chinese Pharmacopeia, Japanese Pharmacopoeia (JP), and German Pharmacopoeia (Deutsches Arzneibuch – DAB);
2) veterinary Pharmacology textbooks and veterinary drug handbooks
Cas No.: 10361-46-3
Synonyms: Albutannin; Albutannins; Tannalbin; Tannalbins; Tannin albuminate; Albumintannate
Typical Physical Properties Physical appearance:White Microgranules
Unique Characteristics and Functions:
Intestinal convergence: it insures the completeness of animals’ mucosa, effectively reduces the rates of diarrhea and promotes the animal production performance & the feed conversion efficiency.
- Neutralizing the enterotoxins of Escherichia coli (LT) and the exotoxin produced by other bacteria, thence to control diarrhea.
- Easy to use: Pro-Tan® employs tannin acid of a special structure, which is different from the free (isolated) tannin acid. Having no irritation to the operators’ skin, it brings great convenience in production and operation; it does not distain the feed processing machines; when added into feed, it does not blacken in touch with water; meanwhile, the tannin acid is stablized consequently.
- Absolutely palatable: Tannalbin is insoluble in water. Tannic acid is only released on condtition that the GUT is alkaline. Therefore the palatability problem is out of the question; It enables the intestinal tract to achieve a target release and a double anti-diarrheal effect of the free tannin acid [1 Kg Pro-Tan® (50%) = 1.5 Kg free tannin acid (70%)].
- High-performance alternative or supplement: Pro-Tan® can completely substitute antibiotic growth promoters (AGPs) and/or high-dose ZnO or spray-dried animal plasma (SDPP) while they are forbidden or during the “No-Antibiotics Feed” period.
- GRAS Substances: Pro-Tan® can be administered to all animal subjects at any growth stages, without withdrawal periods.
Feeding Trials with Adminstration of Pro-tan®
Table 1. The effect of Pro-tan add into the creep feed
①The dose regimen of the control group:ZnO 2250ppm + Bacillus sulfate 20ppm + chlortetracycline 75ppm; The dose regimen of “Pro-tan” group: ZnO 2250ppm + chlortetracycline 75ppm +Pro-tan 1500ppm. ②Test location: Insighter animal experiment farm (Jiangmen,Guangdong); ③Time of the experiment:6th.,May~16th,May.,2015. ④Animal for experiment: Duroc dasanyuan hybrid piglet,25 days of age; ⑤Feed: Custom creep feed, nutritious level: simple protein≥18.0%, crude fiber ≤4.0%，crude ash≤7.0%，calcium 0.5-1.2%，total phosphorus≥0.55%，Lys≥1.5%，DE 3500kcal/kg。（It including 5% SDPP on both of group ）
Table 2. The effect that Pro-tan replace the SDPP when add into the creep feed
Remark：①The dose regimen of the SDPP group：SDPP 5%；ZnO 2250ppm+Bacillus Sulfate 20ppm+chlortetracycline 75ppm；The dose regimen of the Pro-tan group：Choice the equal amount of SPC to replace the SDPP ；ZnO 2250ppm+Bacillus Sulfate 20ppm +chlortetracycline 75ppm+Pro-tan 10000ppm。②Place of examination：The animal examination farm of Ingishter（Jiangmen,Guangdong）；③Examination Date：8th.,~18th.,June.；④Animal for experiment: ：Duroc dasanyuan hybrid piglet,25 days of age;；⑤Feed：custom creep feed，nutritious level：simple protein≥18.0%，crude fiber≤4.0%，crude ash≤7.0%，calcium 0.5-1.2%，total phosphorus≥0.55%，Lys≥1.5%，DE 3500kcal/kg。
Table 3 The effect of Pro-tan on the piglet nursery stage
Remark：The dose regimen of the control group：ZnO 2250ppm+Bacillus Sulfate 20ppm+Chlortetrackcline 75ppm；“The dose regimen of Pro-tan group：（ZnO）2250ppm+Bacillus Sulfate 20ppm+Chlortetrackcline 75ppm+Pro-tan 1000ppm。②Place of Examination :The animal examination farm of Insighter (Jiangmen, Guangdong)；③Date of examination：16th.,May~30th.,May.,2015；④The pig for examination：Duroc dasanyuan hybrid piglet,35 days of age；⑤Feed：Custom nursery feed powder, nutritious level ：simple protein≥18.0%，DE 3500kcal/kg.
Table 4 The effect of Pro-tan in the piglet station
Remark：①The dose regimen of the control group：Cu 200ppm（TBCC）+Bacillus Sulfate 20ppm+Chlortetrackcline 75ppm+Quincetone 50ppm；The dose regimen of Pro-tan Group：Cu 200ppm（TBCC）+Bacillus Sulfate 20ppm+Chilortetrackcline 75ppm+Quincetone 50ppm +Pro-tan 500ppm；②Place of examination：The animal examination farm of Insighter（jiangmen,Guangdong）；③The date of examinate：30th My~29th. June.., 2015；④Animal for examinate：Duroc dasanyuan hybrid pig，in 49 days of age。⑤Feed：Custom commercial piggy feed powder, no any ZnO and AGPs feed additives.
Table 5 The treatment effect of Pro-tan for piglet early weaning diarrhea
Remark：No feeding wean piglet for the feed powder without any AGPs,ZnO and Cu 3 days before the examination. Only choice the diarrhea wean piglet ( in 35 days of age) for examination。①The dose regimen of the control group：No any ZnO,Cu and AGPs additive；The dose regimen of Pro-tan Group：Pro-tan 10kg/t；②Place of examination: the examination farm of Insighte (Jiangmen, Guangdong)；③Date of Examination：May.,D1（The first day for treatment）；D2（The second day for treatment）……
Table 6 The effect of Pro-tan for Broiler
Remark：①The dose regimen of control group：Bacillus sulfate 20ppm+STAFAC 40g/t(1-21 days of age)，Bacillus Sulfate 20ppm+STAFAC 20g/t(22-56 days of age；The dose regimen of Pro-tan Group：Pro-tan 300g/t(1-21 days of age) or 200 g/t(22-56 days of age)；②Place of examination：Animal examination farm of Insighter( Jiangmen,Guangdong）；③Date of examination：2nd.,April~27th May. 2015 ；④Animal for examination：Quick rhubarb feather broiler, the examination period is 56 days。⑤Feed: Custom commercial broiler fee, without any AGPs.
How to use
The protein of Pro-tan is mainly made of the IgY form the highly immune eggand others. It could replace the SDDP when add into the Creep feed (1kg replace 5 kg, the simple protein (SPC,EFFS or FSBM )to replace the common protein in equal level. It could replace forall porcine peptom and whey powder and Fish meal on the nursery stage; it could replace fish meal on the piglet stage.
The quantity of doses recommend:
