Research Grade Sozinibercept
一、中文名稱：
Research Grade Sozinibercept，科研級(jí)Sozinibercept
二、產(chǎn)品描述
Sozinibercept 在血管生成研究中作用關(guān)鍵。探索腫瘤生長與轉(zhuǎn)移機(jī)制時(shí)，它能特異性阻斷 VEGFC、VEGF - D 與 VEGFR - 3 的結(jié)合，抑制腫瘤相關(guān)淋巴管生成。在乳腺癌模型中，使用它可降低腫瘤細(xì)胞通過淋巴管轉(zhuǎn)移的幾率，為腫瘤轉(zhuǎn)移防治策略研究提供依據(jù)。在眼科疾病研究方面，針對(duì)濕性年齡相關(guān)性黃斑變性（wAMD）的研究顯示，Sozinibercept 能抑制脈絡(luò)膜新生血管形成，調(diào)節(jié)相關(guān)信號(hào)通路，減少新生血管，為 wAMD 治療方法探索提供新方向。在傷口愈合研究中，Sozinibercept 參與調(diào)節(jié)血管新生和重塑。在皮膚創(chuàng)傷模型實(shí)驗(yàn)中，使用它可使傷口處血管生成更有序，促進(jìn)傷口快速愈合，為理解組織修復(fù)機(jī)制提供思路。
三、產(chǎn)品詳情
名稱：Research Grade Sozinibercept，科研級(jí)Sozinibercept
貨號(hào)：DHE70402
表達(dá)系統(tǒng)：Mammalian Cells
種屬反應(yīng)性：Human
同種型：Vascular Endothelial Growth Factor Receptor 3 fusion protein with IgG1 Fc Fragment.
克隆類型：Monoclonal
靶標(biāo)：Vascular endothelial growth factor C, VEGFC, Flt4-L, VEGF-C, Vascular endothelial growth factor-related protein, VRP, Flt4 ligand, Vascular endothelial growth factor D, VEGF-D, FIGF, VEGFD, c-Fos-induced growth factor
濃度：1 mg/ml
內(nèi)毒素水平：Please contact with the lab for this information.
純度：>95% as determined by SDS-PAGE.
純化方式：Protein A/G purified from cell culture supernatant.
Accession 號(hào)：P49767 & O43915
克隆號(hào)：Sozinibercept
應(yīng)用：Research Grade Biosimilar
狀態(tài)：Liquid
保存溶液：0.01M PBS, pH 7.4.
穩(wěn)定性和存儲(chǔ)：Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
別名：OPT-302, soluble VEGFR-3, sozinibercept, VGX-300
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