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Postion:Product Catalog >AMG PERK 44
AMG PERK 44
  • AMG PERK 44

AMG PERK 44 NEW

Price $52 $123 $198
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: AMG PERK 44 CAS No.: 1883548-84-2
Purity: ≥98% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAMG PERK 44
DescriptionAMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy. It also inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM), making it useful for cancer research.
In vitroAMG PERK 44 exhibits significant inhibitory activity against pPERK cells in vitro, with an IC50 of 84 nM[1].
In vivoIn four- to six-week-old naive athymic nude mice, AMG PERK 44 (3, 10, 30, 100 mg/kg; orally) robustly inhibited PERK autophosphorylation[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 15 mg/mL (26.73 mM), Sonication is recommended.
KeywordsAMG PERK 44
Inhibitors RelatedStavudine | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Oxyresveratrol | Paeonol | Naringin | Gefitinib
Related Compound LibrariesBioactive Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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