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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >HYDROXY ITRACONAZOLE

HYDROXY ITRACONAZOLE

HYDROXY ITRACONAZOLE Suppliers list
Company Name: Biochempartner
Tel: 0086-13720134139
Email: candy@biochempartner.com
Products Intro: Product Name:Hydroxy Itraconazole
CAS:112559-91-8
Purity:98% HPLC LCMS Package:10G;20G
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:Hydroxy Itraconazole
CAS:112559-91-8
Purity:99% Package:5KG;1KG Remarks:C35H40Cl2N8O4
Company Name: Standardpharm Co. Ltd.
Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Products Intro: Product Name:Itraconazole Impurity 8(Hydroxy Itraconazole)
CAS:112559-91-8
Purity:0.99 Package:10mg;25mg;50mg;100mg
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:Hydroxy Itraconazole
CAS:112559-91-8
Purity:> 95% Package:5mg Remarks:BOC Sciences also provides custom synthesis services for Hydroxy Itraconazole.
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:HYDROXY ITRACONAZOLE
CAS:112559-91-8
Purity:0.99summer Package:5KG;1KG Remarks:Summer 618

HYDROXY ITRACONAZOLE manufacturers

HYDROXY ITRACONAZOLE Basic information
Product Name:HYDROXY ITRACONAZOLE
Synonyms:HYDROXY ITRACONAZOLE;3H-1,2,4-Triazol-3-one, 4-4-4-4-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethoxyphenyl-1-piperazinylphenyl-2,4-dihydro-2-(2-hydroxy-1-methylpropyl)-;4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-methylpropyl)-3H-1,2,4-triazol-3-one;R 63373;4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-Methylpropyl)-;Itraconazole 2-Hydroxy Metabolite;Itraconazole metabolite Hydroxy Itraconazole;Itraconazole Impurity 8(Hydroxy Itraconazole)
CAS:112559-91-8
MF:C35H38Cl2N8O5
MW:721.63
EINECS:
Product Categories:Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Various Metabolites and Impurities;Isotooe labelled metabolites;metabolites;Isotopically Labeled Pharmaceutical Reference Standard
Mol File:112559-91-8.mol
HYDROXY ITRACONAZOLE Structure
HYDROXY ITRACONAZOLE Chemical Properties
Melting point 76-78°C
Boiling point 884.7±75.0 °C(Predicted)
density 1.44±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka14.72±0.20(Predicted)
color White to Pale Beige
Safety Information
MSDS Information
HYDROXY ITRACONAZOLE Usage And Synthesis
DescriptionHydroxy itraconazole (OH-ITZ) is an active metabolite of the antifungal agent itraconazole . Itraconazole is metabolized by the cytochrome P450 isoform 3A4 (CYP3A4) to form hydroxy itraconazole. Hydroxy itraconazole exhibits in vitro antifungal activity (MIC = 0.019, 0.078, and 0.078 mg/ml against C. albicans, A. fumigatus, and C. neoformans, respectively). Plasma concentration of hydroxy itraconazole is directly correlated to that of the parent compound and is used as an indicator of prophylaxis for fungal infections.
Chemical PropertiesOff-White Crystalline Solid
UsesA metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. It is a COVID19-related research product.
HYDROXY ITRACONAZOLE Preparation Products And Raw materials
Tag:HYDROXY ITRACONAZOLE(112559-91-8) Related Product Information
Itraconazole 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE trans-Itraconazole N-Desalkyl Itraconazole Itraconazole Impurity 34 Butyl Itraconazole KETO ITRACONAZOLE 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl benzoate Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole Propyl Itraconazole (1,2,4-Triazol-4-yl) Itraconazole cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl methanesulphonate Itraconazole Impurity 15 cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate

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