- Engeletin
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- $41.00 / 5mg
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2025-05-09
- CAS:572-31-6
- Min. Order:
- Purity: 99.72%
- Supply Ability: 10g
- Engeletin
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- $0.00 / 20mg
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2023-02-24
- CAS:572-31-6
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one Basic information |
Product Name: | (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one | Synonyms: | (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one;(+)-(2R,3R)-Dihydrokaempferol 3-O-alpha-L-rhamnoside;(2R,3R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside;Dihydrokaempferol 3-O-alpha-L-rhamnopyranoside;Dihydrokaempferol 3-rhamnoside;Engelitin;AroMadendrin 3-rhaMnoside;3-((6-Deoxy-alpha-L-Mannopyranosyl)oxy)-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one(2R-trans) | CAS: | 572-31-6 | MF: | C21H22O10 | MW: | 434.39 | EINECS: | 300-009-2 | Product Categories: | standardized herbal extract;reference standards from Chinese medicinal herbs (TCM).;phytochemical;pharmaceutical intermediate;chemical reagent | Mol File: | 572-31-6.mol | ![(2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one Structure](CAS/GIF/572-31-6.gif) |
| (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one Chemical Properties |
Melting point | 176-177℃ | Boiling point | 763.4±60.0 °C(Predicted) | density | 1.66 | storage temp. | -20°C | solubility | DMSO:93.0(Max Conc. mg/mL);214.09(Max Conc. mM) | pka | 7.37±0.60(Predicted) | form | powder | color | White | optical activity | [α]/D -13 to -17°, c =0.5 in pyridine |
| (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one Usage And Synthesis |
Uses | Engeletin is a polyphenol compound used as an anti-oxidant. | Biological Activity | New MCE product August 2018. Engeletin is a flavanonol glycoside present in the skin of white grapes and white wine th at exhibits anti-inflammatory activities. It inhibits LPS induced cytokines production in mouse J774A.1 macrophages. Also, engeletin attenuates LPS-induced endometritis in mice through inhibiting NF-KB activation, and inhibits inflammatory response in LPS-induced acute lung injury (ALI). | in vivo | Engeletin (25, 50, 100 mg/kg, i.p.) markedly reduces LPS-increased myeloperoxidase activity in mice, activates NF-κB-pathway activation, decreases the production of inflammatory mediators (iNOS and COX-2), and suppresses the expression of TLR4-signaling downstream molecules such as MyD88, IRAK1, TRAF6, and TAK1 proteins[1]. | IC 50 | NF-κB |
| (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one Preparation Products And Raw materials |
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