| Company Name: |
BOC Sciences
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| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:MK-0359
CAS:346629-30-9
Purity:≥98% Remarks:MK-0359 is a selective and potent oral PDE4 inhibitor with in vivoefficacy in animal models of asthma and cognition.
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| Company Name: |
Absin Bioscience Inc.
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| Tel: |
021-38015121 18438616290 |
| Email: |
wulan@absin.cn |
| Products Intro: |
Product Name:MK-0359
CAS:346629-30-9
Purity:>98% Package:5mg;10mg
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6-(1-METHANESULFONYL-1-METHYL-ETHYL)-8-(3-[(E)-2-(4-METHANESULFONYL-PHENYL)-2-(3-METHYL-[1,2,4]OXADIAZOL-5-YL)-VINYL]-PHENYL)-QUINOLINE manufacturers
- MK-0359
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- $2500.00 / 100mg
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2024-10-28
- CAS:346629-30-9
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 6-(1-METHANESULFONYL-1-METHYL-ETHYL)-8-(3-[(E)-2-(4-METHANESULFONYL-PHENYL)-2-(3-METHYL-[1,2,4]OXADIAZOL-5-YL)-VINYL]-PHENYL)-QUINOLINE Basic information |
| Product Name: | 6-(1-METHANESULFONYL-1-METHYL-ETHYL)-8-(3-[(E)-2-(4-METHANESULFONYL-PHENYL)-2-(3-METHYL-[1,2,4]OXADIAZOL-5-YL)-VINYL]-PHENYL)-QUINOLINE | | Synonyms: | 6-(1-METHANESULFONYL-1-METHYL-ETHYL)-8-(3-[(E)-2-(4-METHANESULFONYL-PHENYL)-2-(3-METHYL-[1,2,4]OXADIAZOL-5-YL)-VINYL]-PHENYL)-QUINOLINE;L-454,560;QUINOLINE, 6-[1-METHYL-1-(METHYLSULFONYL)ETHYL]-8-[3-[(1E)-2-(3-METHYL-1,2,4-OXADIAZOL-5-YL)-2-[4-(METHYLSULFONYL)PHENYL]ETHENYL]PHENYL]-;MK-0359;3-methyl-5-[(E)-1-(4-methylsulfonylphenyl)-2-[3-[6-(2-methylsulfonylpropan-2-yl)quinolin-8-yl]phenyl]ethenyl]-1,2,4-oxadiazole;L-454560; MK 0359; MK0359 | | CAS: | 346629-30-9 | | MF: | C31H29N3O5S2 | | MW: | 587.71 | | EINECS: | | | Product Categories: | | | Mol File: | 346629-30-9.mol | ![6-(1-METHANESULFONYL-1-METHYL-ETHYL)-8-(3-[(E)-2-(4-METHANESULFONYL-PHENYL)-2-(3-METHYL-[1,2,4]OXADIAZOL-5-YL)-VINYL]-PHENYL)-QUINOLINE Structure](CAS/GIF/346629-30-9.gif) |
| | 6-(1-METHANESULFONYL-1-METHYL-ETHYL)-8-(3-[(E)-2-(4-METHANESULFONYL-PHENYL)-2-(3-METHYL-[1,2,4]OXADIAZOL-5-YL)-VINYL]-PHENYL)-QUINOLINE Chemical Properties |
| Melting point | 201-203 °C | | Boiling point | 839.4±75.0 °C(Predicted) | | density | 1.315±0.06 g/cm3(Predicted) | | pka | 3?+-.0.20(Predicted) |
| | 6-(1-METHANESULFONYL-1-METHYL-ETHYL)-8-(3-[(E)-2-(4-METHANESULFONYL-PHENYL)-2-(3-METHYL-[1,2,4]OXADIAZOL-5-YL)-VINYL]-PHENYL)-QUINOLINE Usage And Synthesis |
| Uses | MK-0359 (L-454,560) is a selective and orally active PDE4 inhibitor, and can be used for asthma and chronic obstructive pulmonary disease (COPD) research[1]. | | References | [1] Lu S, et al. Randomized, placebo-controlled study of a selective PDE4 inhibitor in the treatment of asthma. Respir Med. 2009 Mar;103(3):342-7. DOI:10.1016/j.rmed.2008.10.024 |
| | 6-(1-METHANESULFONYL-1-METHYL-ETHYL)-8-(3-[(E)-2-(4-METHANESULFONYL-PHENYL)-2-(3-METHYL-[1,2,4]OXADIAZOL-5-YL)-VINYL]-PHENYL)-QUINOLINE Preparation Products And Raw materials |
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