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Product Name:JTE 013;1-[1,3-DiMethyl-4-(2-Methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-4-(3,5-dichloro-4-pyridinyl)-seMicarbazide CAS:547756-93-4 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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EMMX Biotechnology LLC
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888-539-0666 |
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Product Name:JTE 013 CAS:547756-93-4 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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BOC Sciences
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Product Name:1-(3,5-Dichloropyridin-4-yl)-3-[(1,3-dimethyl-4-propylpyrazolo[3,4-b]pyridin-6-yl)amino]urea CAS:547756-93-4 Purity:>=98% by HPLC Remarks:Reach out to us for more information about custom solutions.
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amyjetsci
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Product Name:JTE-013 Package:15ml/
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| 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Basic information |
Product Name: | 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE | Synonyms: | N-(2,6-Dichloropyridin-4-yl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazinecarboxamide;1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE;JTE 013;1-(3,5-Dichloropyridin-4-yl)-3-[(1,3-dimethyl-4-propylpyrazolo[3,4-b]pyridin-6-yl)amino]urea | CAS: | 547756-93-4 | MF: | C17H19Cl2N7O | MW: | 408.28506 | EINECS: | | Product Categories: | Lysophospholipid receptor and related | Mol File: | 547756-93-4.mol | ![1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Structure](CAS/GIF/547756-93-4.gif) |
| 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Chemical Properties |
storage temp. | Store at +4°C |
| 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Usage And Synthesis |
Uses | JTE 013 is an antagonist of Sphingosine-1-Phosphate Receptor-2 (S1P2R). | Biological Activity | Sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P 2 (EDG-5). Inhibits S1P binding to human S1P 2 receptors with an IC 50 value of 17.6 nM. At concentrations up to 10 μ M, displays 4.2% inhibition of S1P 3 and does not antagonize S1P 1 . Enhances S1P-induced angiogenesis in vivo . |
| 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Preparation Products And Raw materials |
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