- Levosulpiride
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- $50.00 / 100mg
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2024-11-19
- CAS:23672-07-3
- Min. Order:
- Purity: 99.93%
- Supply Ability: 10g
- Levosulpiride
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- $35.00/ kg
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2024-03-16
- CAS:23672-07-3
- Min. Order: 1kg
- Purity: 99.8%
- Supply Ability: 200tons/year
- Levosulpiride
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- $45.00/ kg
-
2024-01-16
- CAS:23672-07-3
- Min. Order: 1kg
- Purity: 99.8%
- Supply Ability: 200tons/year
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| | Levosulpiride Basic information |
| | Levosulpiride Chemical Properties |
| Melting point | 183-186 °C(lit.) | | density | 1.236±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF (Slightly), DMSO (Slightly), Methanol (Slightly) | | pka | 9.98±0.60(Predicted) | | form | Solid | | color | White to Off-White | | Merck | 14,8989 | | InChIKey | BGRJTUBHPOOWDU-NSHDSACASA-N | | CAS DataBase Reference | 23672-07-3(CAS DataBase Reference) |
| RIDADR | 3077 | | WGK Germany | 3 | | RTECS | BZ3400100 | | HS Code | 29350090 | | Toxicity | LD50 oral in rabbit: > 1500mg/kg |
| | Levosulpiride Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | (S)-(?)-Sulpiride was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels10 and on depression-like behavior in ovariectomized female rats.11 | | Uses | dopamine receptor antagonists | | Uses | Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic. | | Definition | ChEBI: An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4,
1 and D5 receptors respectively). | | General Description | (S)-(?)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders. | | Biological Activity | Active enantiomer. Selective D 2 -like dopamine antagonist (K i values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 μ M at D 2 , D 3 , D 4 , D 1 and D 5 receptors respectively). | | Biochem/physiol Actions | (S)-(?)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2 receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8 Since dopamine controls human sexual function, (S)-(?)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9 | | storage | Room temperature |
| | Levosulpiride Preparation Products And Raw materials |
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