| | 2-Diethylaminoethylchloride hydrochloride Basic information |
| Product Name: | 2-Diethylaminoethylchloride hydrochloride | | Synonyms: | 3,5-DIMETHOXYANISOLE;(2-chloroethyl)diethylaminemonohydrochloride;1-chloro-2-(diethylamine)ethanehydrochloride;2-chloroethyl-n,n-diethylaminehydrochloride;TRISMETHOXYBENZENE;2-chloro-n,n-diethyl-ethanaminhydrochloride;2-Chlorotriethylaminehydrochl;2-chloro-triethylaminhydrochloride | | CAS: | 869-24-9 | | MF: | C6H15Cl2N | | MW: | 172.1 | | EINECS: | 212-786-4 | | Product Categories: | Aliphatics;Miscellaneous Reagents | | Mol File: | 869-24-9.mol |  |
| | 2-Diethylaminoethylchloride hydrochloride Chemical Properties |
| Melting point | 50-53 °C(lit.) | | Boiling point | 255 °C(lit.) | | density | 1.1919 (rough estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | 1.6000 (estimate) | | Fp | 186 °F | | storage temp. | Poison room | | solubility | methanol: 0.1 g/mL, clear, colorless | | form | Crystalline Powder | | color | White to slightly beige | | PH | 5 (100g/l, H2O, 20℃) | | Water Solubility | 2000 g/L (20 ºC) | | Sensitive | Moisture Sensitive | | BRN | 3591991 | | Stability: | Hygroscopic, Moisture Sensitive | | InChIKey | RAGSWDIQBBZLLL-UHFFFAOYSA-N | | CAS DataBase Reference | 869-24-9(CAS DataBase Reference) | | EPA Substance Registry System | Diethyl-(2-chloroethyl)amine hydrochloride (869-24-9) |
| | 2-Diethylaminoethylchloride hydrochloride Usage And Synthesis |
| Chemical Properties | 2-Diethylaminoethylchloride hydrochloride is colourless to beige crystals | | Uses | 2-Chloro-N,N-diethylethylamine hydrochloride (65% in water) (DEC 65) is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet | | Uses | 2-Chloro-N,N-diethylethylamine hydrochloride can be used as an alkylating reagent for the synthesis of:
- Substituted oxindole derivatives to be used as growth hormone secretagogs.
- 1-Substituted-5,6-dinitrobenzimidazoles with antimicrobial and antiprotozoal activities.
- Thiophene containing triarylmethane (TRAM) derivatives to be used as antitubercular agents.
- Tris(2-(diethylamino)ethyl)amine to be used as a catalyst in combination with CuBr (Et6TREN/CuBr) for atom transfer radical polymerization of n-butyl acrylate.
It can also be used for the derivatization of chitosan to incorporate aminofunctionality onto it at C-6 position. | | Uses | 2-Diethylaminoethylchloride hydrochloride is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet | | Purification Methods | Crystallise the salt from absolute MeOH (to remove highly coloured impurities). [Beilstein 4 III 240.] |
| | 2-Diethylaminoethylchloride hydrochloride Preparation Products And Raw materials |
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