鐮葉芹二醇
| 中文名稱 | 鐮葉芹二醇 |
|---|---|
| 中文同義詞 | 鐮葉芹二醇;發(fā)卡二醇;(3R,8S,Z)-十七碳-1,9-二烯-4,6-二炔-3,8-二醇;(+)-(3R,8S)-鐮葉芹二醇;鐮葉芹二醇,法卡林二醇,福爾卡烯炔二醇,(3R,3S|)-法卡林二醇;FALCARINDIOL|||鐮葉芹二醇;化合物:(+)-(3R,8S)-Falcarindiol;化合物：(+)-(3R,8S)-Falcarindiol |
| 英文名稱 | Falcarindiol |
| 英文同義詞 | 1,9-Heptadecadiene-4,6-diyne-3,8-diol,(3R,8S,9Z)-;(3R,8S)-Falcarindiol;3(R),8(S),9(Z)-Falcarindiol;(3R,8S,9Z)-1,9-Heptadecadiene-4,6-diyne-3,8-diol;Falcarindiol/(3R),(8S)-Falcarindiol;8S)-Falcarindiol;(+)-(3R,8S)-falcarindiol;(3R,8S,Z)-Heptadeca-1,9-dien-4,6-diyne-3,8-diol |
| CAS號(hào) | 225110-25-8 |
| 分子式 | C17H24O2 |
| 分子量 | 260.37 |
| EINECS號(hào) | |
| 相關(guān)類別 | 標(biāo)準(zhǔn)品-對(duì)照品;對(duì)照品;標(biāo)準(zhǔn)品 -中藥標(biāo)準(zhǔn)品;標(biāo)準(zhǔn)品;Aliphatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol文件 | 225110-25-8.mol |
| 結(jié)構(gòu)式 |  |
鐮葉芹二醇 性質(zhì)
| 沸點(diǎn) | 408.2±45.0 °C(Predicted) |
|---|---|
| 密度 | 1.000±0.06 g/cm3(Predicted) |
| 儲(chǔ)存條件 | Store at -20°C |
| 溶解度 | 溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。 |
| 形態(tài) | 油狀 |
| 酸度系數(shù)(pKa) | 11.65±0.20(Predicted) |
| 顏色 | Colorless to light yellow |
Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) 是一種天然的聚乙炔化合物，存在于傘形科的許多植物中。Falcarindiol 可抑制LPS刺激的 inducible nitric oxide synthase (iNOS)、tumor necrosis factor alpha (TNFα)、interleukin-6 (IL-6) 和 interleukin-1 beta (IL-1β) 的表達(dá)。Falcarindiol 可減弱LPS誘導(dǎo)的 JNK、ERK、STAT1 和 STAT3 信號(hào)分子的激活。Falnidamol 是一種具有抗癌活性的嘧啶嘧啶類化合物。
| Target | Value |
|
iNOS
() | |
|
TNFα
() | |
|
IL-6
() | |
|
IL-1β
() | |
|
JNK
() | |
|
|
用途
用于含量測(cè)定/鑒定/藥理實(shí)驗(yàn)等。用途
Falcarindiol was isolated as an algicidal principle against the harmful red tide dinoflagellate, Heterocapsa circularisquama, from Notopterygii Rhizoma through bioassay-guided separation.To determine
the ambiguous absolute structure of this active principle, all three stereoisomers as well as falcarindiol were synthesized. 聽As a result of intensive analytical of their physicochemical properties, t
he configuration of Falcarinfiol was revealed to be 3R,8S. 聽(3S,8S)- and (3S,8R)-isomers were found to exhibit more potent algicidal activity than (3R,8S)-Falcarindiol isolated from Notopterygii Rhizo
ma.安全信息
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2025/05/22 | HY-N1976 | 鐮葉芹二醇 (+)-(3R,8S)-Falcarindiol | 225110-25-8 | 1 mg | 500元 |
| 2025/05/22 | HY-N1976 | 鐮葉芹二醇 (+)-(3R,8S)-Falcarindiol | 225110-25-8 | 5 mg | 1500元 |