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| | 2-Amino-6-fluorobenzothiazole Basic information | | Structure |
| | 2-Amino-6-fluorobenzothiazole Chemical Properties |
| Melting point | 183-185 °C (lit.) | | Boiling point | 312.0±34.0 °C(Predicted) | | density | 1.3490 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Crystalline Powder | | pka | 3.77±0.10(Predicted) | | color | Off-white to tan | | InChI | InChI=1S/C7H5FN2S/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H,(H2,9,10) | | InChIKey | CJLUXPZQUXVJNF-UHFFFAOYSA-N | | SMILES | S1C2=CC(F)=CC=C2N=C1N | | CAS DataBase Reference | 348-40-3(CAS DataBase Reference) |
| | 2-Amino-6-fluorobenzothiazole Usage And Synthesis |
| Structure | Crystals of 2-amino-6-fluoro-1,3-benzothiazole, C7H5FN2S, have an amphiphilic layer-like structure. Each amino substituent donates two protons to hydrogen bonds and accepts one. The ring N atoms accept one proton. The F atoms are not involved in any hydrogen bonds. | | Chemical Properties | off-white to tan crystalline powder | | Uses | 2-Amino-6-fluorobenzothiazole is a useful research chemical. An intermediate for the synthesis of benzothiazoles and aminobenzothiazoles with antimicrobial activity. | | Definition | ChEBI: 6-Fluoro-1,3-benzothiazol-2-amine is a member of benzothiazoles. | | Application | 2-Amino-6-fluorobenzothiazole (AFBT) can be used for:
(1) Interaction of AFBT with β-cyclodextrin (β-CDx) in aqueous and solid state. The proton transfer behaviour of AFBT in aqueous and β-CDx solutions was studied.
(2) Spectroscopic studies. Fourier transform infrared spectroscopy (4000-400 cm-1) and Fourier transform Raman spectroscopy (4000-100 cm-1) measurements were carried out on AFBT to investigate the effect of fluorine and amino groups on the backbone pattern and proton chemical shifts. |
| | 2-Amino-6-fluorobenzothiazole Preparation Products And Raw materials |
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