| Company Name: |
ShangHai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847 13636370518 |
| Email: |
shyysw007@163.com |
| Products Intro: |
Product Name:saikogenin A
CAS:5092-09-1
Purity:HPLC>=98% Package:5mg Remarks:B23137
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saikogenin A manufacturers
- Saikogenin A
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- $198.00 / 1mg
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2024-11-19
- CAS:5092-09-1
- Min. Order:
- Purity: 99.47%
- Supply Ability: 10g
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| | saikogenin A Basic information |
| Product Name: | saikogenin A | | Synonyms: | Oleana-11,13(18)-diene-3,16,23,28-tetrol, (3β,4α,16β)-;Clinopodiside A1;Saikogenin A,inhibit,Inhibitor,DPP,1166100,Dipeptidyl Peptidase;Saikogenin A, 10 mM in DMSO | | CAS: | 5092-09-1 | | MF: | C30H48O4 | | MW: | 472.7 | | EINECS: | | | Product Categories: | | | Mol File: | 5092-09-1.mol |  |
| | saikogenin A Chemical Properties |
| Melting point | 287-293 °C | | Boiling point | 607.4±55.0 °C(Predicted) | | density | 1.16±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 14.47±0.70(Predicted) | | color | White to off-white |
| | saikogenin A Usage And Synthesis |
| Biological Activity | Saikogenin A, extracted from the traditional Chinese medicine Bupleurum, is a dipeptidyl peptidase IV (DPP-IV) inhibitor. | | Biochem/physiol Actions | Saikogenin A is a naturally occurring plant extract that has been shown to have a variety of biological activities. saikogenin A has anti-inflammatory and tumour cell growth inhibiting effects. Its anti-inflammatory effect is due to an increase in corticosterone caused by the release of ACTH and has a direct effect on the inflammatory process. It also inhibits the absorption of ultraviolet light by human skin cells and erythromycin-induced UvB damage. | | in vitro | Saikogenin A has certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6%. DPP-IV is a non-classical serine aminopeptidase from its amino terminus of polypeptides and proteins (N-terminus) removing Xaa-Pro dipeptide. | | in vivo | Saikogenin A, an anti-inflammatory drug, is present in the crude extract of a Chinese herbal plant called Tsai-Fu. It is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema . The anti-inflammatory action of it are due to an increase in corticosterone caused by the release of arenocorticotropic hormone (ACTH) and a direct effect on the process of inflammation. | | target | |
| | saikogenin A Preparation Products And Raw materials |
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