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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
2,5-DIMETHYLBENZALDEHYDE (DNPH DERIVATIVE) 2,5-DIMETHYLBENZALDEHYDE (DNPH DERIVATIVE) 152477-96-8 C15H14N4O4
ENDRIN KETONE ENDRIN KETONE 53494-70-5 C12H8Cl6O
PERTUSSIS TOXIN PERTUSSIS TOXIN 70323-44-3 NULL
1-methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine 1-methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine 7081-40-5 C20H23NS
ESPROCARB ESPROCARB 85785-20-2 C15H23NOS
MECOPROP-P MECOPROP-P 16484-77-8 C10H11ClO3
BENZYLIDENE CAMPHOR BENZYLIDENE CAMPHOR 15087-24-8 C17H20O
ECGONIDINE METHYL ESTER MESYLATE ECGONIDINE METHYL ESTER MESYLATE 43021-26-7 C10H15NO2
ZERANOL ZERANOL 55331-29-8 C18H26O5
11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE 641-77-0 C21H30O4
BROMOBUTIDE BROMOBUTIDE 74712-19-9 C15H22BrNO
ANTHRANILIC ACID ISOPROPYLAMIDE ANTHRANILIC ACID ISOPROPYLAMIDE 30391-89-0 C10H14N2O
2-METHYLCHRYSENE 2-METHYLCHRYSENE 3351-32-4 C19H14
THIOXANTHENE THIOXANTHENE 261-31-4 C13H10S
ALPHA-ZEARALENOL ALPHA-ZEARALENOL 36455-72-8 C18H24O5
(+)-(1R,2R)-O-DESMETHYL TRAMADOL HCL (+)-(1R,2R)-O-DESMETHYL TRAMADOL HCL 148262-77-5 C15H24ClNO2
TETRADECANOIC-D27 ACID TETRADECANOIC-D27 ACID 60658-41-5 C14HD27O2
OXYMORPHONE OXYMORPHONE 76-41-5 C17H19NO4
ANDROSTERONE ACETATE ANDROSTERONE ACETATE 1164-95-0 C21H32O3
DIBENZ(A,J)ACRIDINE DIBENZ(A,J)ACRIDINE 224-42-0 C21H13N
2,4'-DINITRODIPHENYLAMINE 2,4'-DINITRODIPHENYLAMINE 612-36-2 C12H9N3O4
GUGGULSTERONE E GUGGULSTERONE E 39025-24-6 C21H28O2
POTASSIUM PALMITATE POTASSIUM PALMITATE 2624-31-9 C16H33KO2
AROCLOR 1016, 1X5ML, TRANSFORMER OIL 50M G/KG AROCLOR 1016, 1X5ML, TRANSFORMER OIL 50M G/KG 12674-11-2 C12H7Cl3
2,2',4,4'-TETRABROMODIPHENYL ETHER 2,2',4,4'-TETRABROMODIPHENYL ETHER 5436-43-1 C12H6Br4O
DIBENZO(A,J)ANTHRACENE DIBENZO(A,J)ANTHRACENE 224-41-9 C22H14
DMST DMST 66840-71-9 C9H14N2O2S
CHLORTHION CHLORTHION 500-28-7 C8H9ClNO5PS
HEXATETRACONTANE HEXATETRACONTANE 7098-24-0 C46H94
4-(BUTYLAMINO)-1-ETHYL-6-METHYL 1H-PYRAZOLO[3,4B]PYRIDINE-5-ETHYLCARBOXYLATE HYDROCHLORIDE 4-(BUTYLAMINO)-1-ETHYL-6-METHYL 1H-PYRAZOLO[3,4B]PYRIDINE-5-ETHYLCARBOXYLATE HYDROCHLORIDE 41094-88-6 C16H24N4O2
SENKIRKIN SENKIRKIN 2318-18-5 C19H27NO6
2-DIETHYLAMINOETHYL 2-PHENYLBUTYRATE CITRATE SALT 2-DIETHYLAMINOETHYL 2-PHENYLBUTYRATE CITRATE SALT 13900-12-4 C22H33NO9
HENTETRACONTANE HENTETRACONTANE 7194-87-8 C41H84
HYDROCODONE BITARTRATE HYDROCODONE BITARTRATE 143-71-5 C22H27NO9
DELTA-8-THC DELTA-8-THC 5957-75-5 C21H30O2
13-CIS-ACITRETIN 13-CIS-ACITRETIN 69427-46-9 C21H26O3
YTTERBIUM(III) IONOPHORE I YTTERBIUM(III) IONOPHORE I 125110-14-7 C16H17N5O8S2
SQ-NHS* SQ-NHS* 154161-81-6 C34H32ClN3O6
CITALOPRAM  RELATED  COMPOUND  F  (200 MG) (DIMETHYL-(1-METHYL-3,3-DIPHENYL-ALLYL)-AMINE HYDROCHLORIDE) CITALOPRAM RELATED COMPOUND F (200 MG) (DIMETHYL-(1-METHYL-3,3-DIPHENYL-ALLYL)-AMINE HYDROCHLORIDE) 55011-89-7 C18H22ClN
DIHEPTYLTIN DICHLORIDE DIHEPTYLTIN DICHLORIDE 74340-12-8 C14H30Cl2Sn
METHYL DIBROMOACETATE, 50MG, NEAT METHYL DIBROMOACETATE, 50MG, NEAT 6482-26-4 C3H4Br2O2
2-NP-AHD 2-NP-AHD 623145-57-3 C10H8N4O4
EC 2.3.2.2 EC 2.3.2.2 9046-27-9
DIOFENOLAN DIOFENOLAN 63837-33-2 C18H20O4
PROPYLENE GLYCOL DILAURATE PROPYLENE GLYCOL DILAURATE 22788-19-8 C27H52O4
ALODAN ALODAN 2550-75-6 C9H6Cl8
KETOPROFEN-D3 KETOPROFEN-D3 159490-55-8 C16H14O3
2,4,5-T-1-OCTYL ESTER 2,4,5-T-1-OCTYL ESTER 2630-15-1 C16H21Cl3O3
4-(METHYL-D3-NITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL 4-(METHYL-D3-NITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL 1020719-61-2 C10H12D3N3O2
EDDP PERCHLORATE EDDP PERCHLORATE 66729-78-0 C20H24ClNO4
N-DESMETHYLFLUNITRAZEPAM N-DESMETHYLFLUNITRAZEPAM 2558-30-7 C15H10FN3O3
AROCHLOR 1232 AROCHLOR 1232 11100-14-4
PENTANOCHLOR PENTANOCHLOR 2307-68-8 C13H18ClNO
2,4,4'-TRIBROMODIPHENYL ETHER 2,4,4'-TRIBROMODIPHENYL ETHER 41318-75-6 C12H7Br3O
CIS-MEVINPHOS CIS-MEVINPHOS 338-45-4 C7H13O6P
PYRIDATE METABOLITE PYRIDATE METABOLITE 40020-01-7 C10H7ClN2O
PENFLUORON PENFLUORON 35367-31-8 C15H9F5N2O2
APOLIPOPROTEIN A-I, HUMAN APOLIPOPROTEIN A-I, HUMAN
CHLORDIAZEPOXIDE-D5 CHLORDIAZEPOXIDE-D5 65891-81-8 C16H14ClN3O
METHYL TRIBROMOACETATE, 99 METHYL TRIBROMOACETATE, 99 3222-05-7 C3H3Br3O2
GLYBURIDE   RELATED   COMPOUND   B   (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS) GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS) 21165-77-5 C18H19ClN2O6S
Chitosan Hydrochloride Chitosan Hydrochloride 70694-72-3
METFORMIN-D6, HYDROCHLORIDE METFORMIN-D6, HYDROCHLORIDE 1185166-01-1 C4H6ClD6N5
DIBENZ[A,I]ACRIDINE DIBENZ[A,I]ACRIDINE 226-92-6 C21H13N
SODIUM O-IODOHIPPURATE SODIUM O-IODOHIPPURATE 133-17-5 C9H7INNaO3
NAPHTHALENE-13C10 NAPHTHALENE-13C10 219526-41-7 C10H8
ETHYL FORMATE-D1 ETHYL FORMATE-D1 35976-76-2 C3H6O2
N-DESMETHYLCITALOPRAM HYDROCHLORIDE N-DESMETHYLCITALOPRAM HYDROCHLORIDE 144025-14-9 C19H19FN2O
2-(4-chloro-3-sulphamoylbenzoyl)benzoic acid 2-(4-chloro-3-sulphamoylbenzoyl)benzoic acid 5270-74-6 C14H10ClNO5S
5H-dibenzo[a,d]cycloheptene 5H-dibenzo[a,d]cycloheptene 256-81-5 C15H12
1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea dihydrochloride 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea dihydrochloride 5318-76-3 C19H22Cl2N6O
1-tert-butylamino-3-(o-cyclopentylphenoxy)propan-2-ol hydrochloride 1-tert-butylamino-3-(o-cyclopentylphenoxy)propan-2-ol hydrochloride 28163-36-2 C18H30ClNO2
4-THUJANOL 4-THUJANOL 546-79-2 C10H18O
FLUOROIMIDE FLUOROIMIDE 41205-21-4 C10H4Cl2FNO2
3-(2-CHLORO-4-METHYLBENZOYL)-4-PHENYLTHIOBICYCLO[3,2,1]OCT-2-EN-4-ONE 3-(2-CHLORO-4-METHYLBENZOYL)-4-PHENYLTHIOBICYCLO[3,2,1]OCT-2-EN-4-ONE 156963-66-5 C22H19ClO4S2
Methasulfocarb Methasulfocarb 66952-49-6 C9H11NO4S2
6-aminocarbovir 6-aminocarbovir 124752-25-6 C11H14N6O
dihydromevinolin dihydromevinolin 77517-29-4 C24H38O5
1,2-DIPHENYL-3-METHYL-4-[METHYLAMINO]-2-BUTYL PROPIONATE MALEATE SALT 1,2-DIPHENYL-3-METHYL-4-[METHYLAMINO]-2-BUTYL PROPIONATE MALEATE SALT 38910-73-5 C25H31NO6
PACLITAXEL C PACLITAXEL C 153415-45-3 C46H57NO14
2,4-Diamino-6-phenyl-7-pteridinol 2,4-Diamino-6-phenyl-7-pteridinol 19152-93-3 C12H10N6O
1-HYDROXYCLOBUT-1-ENE-3,4-DIONE SODIUM SALT 1-HYDROXYCLOBUT-1-ENE-3,4-DIONE SODIUM SALT 71376-34-6 C4H3NaO3
2-(Carbamoyloxymethyl)-1-methyl-d3-5-nitro-imidazole 2-(Carbamoyloxymethyl)-1-methyl-d3-5-nitro-imidazole 1015855-87-4 C6D3H5N4O4
Dimethenamid-d3 Dimethenamid-d3 1246816-31-8 C12H18ClNO2S
SEBUTHYLAZINE-DESETHYL SEBUTHYLAZINE-DESETHYL 37019-18-4 C7H12ClN5
SPIROTETRAMAT SPIROTETRAMAT 203313-25-1 C21H27NO5
Tapentadol O-β-D-Glucuronide Tapentadol O-β-D-Glucuronide 1300037-86-8 C20H31NO7
2,4,5-T-2-ETHYLHEXYL ESTER 2,4,5-T-2-ETHYLHEXYL ESTER 1928-47-8 C16H21Cl3O3
2,5-DiMethyl Celecoxib 2,5-DiMethyl Celecoxib 457639-26-8 C18H16F3N3O2S
2-(MethylaMino)-3',4'-(Methylenedioxy)valerophenone Hydrochloride 2-(MethylaMino)-3',4'-(Methylenedioxy)valerophenone Hydrochloride 17763-01-8 C13H18ClNO3
FaMotidine AMide IMpurity FaMotidine AMide IMpurity 76824-16-3 C8H13N5OS2
Tapentadol O-Sulfate Tapentadol O-Sulfate 1300037-87-9 C14H23NO4S
1-[3-(DIMETHYLAMINO)PROPYL]-1-(4-FLUOROPHENYL)-1,3-DIHYDRO-5-ISOBENZOFURANCARBOXAMIDE 1-[3-(DIMETHYLAMINO)PROPYL]-1-(4-FLUOROPHENYL)-1,3-DIHYDRO-5-ISOBENZOFURANCARBOXAMIDE 64372-56-1 C20H23FN2O2
Trimethoprim Related Compound A (25 mg) (4-amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-2-ol) (AS) Trimethoprim Related Compound A (25 mg) (4-amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-2-ol) (AS) 60729-91-1 C14H17N3O4
BMS 564929 BMS 564929 627530-84-1 C14H12ClN3O3
BENZO(C)CHRYSENE BENZO(C)CHRYSENE 194-69-4 C22H14
DELPHINIDIN-3-GALACTOSIDE DELPHINIDIN-3-GALACTOSIDE 28500-00-7 C21H21ClO12
Bethoxazin Bethoxazin 163269-30-5 C11H9NO2S2
1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol 1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol 5196-20-3 C8H9NO2
metomidate metomidate 5377-20-8 C13H14N2O2
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