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ChemicalBook >> CAS DataBase List >> D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide

D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide

D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide price.
  • $242 - $347
  • Product name: D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide
  • CAS: 1173671-63-0
  • MF: C20H18N6O
  • MW: 358.4
  • EINECS:
  • MDL Number:MFCD04006470
  • Synonyms:D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide;Rhosin;Rhosin /G04, (2R)-2-Amino-3-(1H-indol-3-yl)-N′-((1E)-quinoxalin-6-ylmethylidene)propanehydrazide;Rho Inhibitor, Rhosin - Calbiochem;Rhosin (G04)
4 prices
Selected condition：
Brand
  • Crysdot
  • CSNpharm
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerCrysdot
  • Product numberCD31004418
  • Product descriptionRhosin 98+%
  • Packaging10mg
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004418
  • Product descriptionRhosin 98+%
  • Packaging5mg
  • Price$243
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN17515
  • Product descriptionRhosin
  • Packaging5mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number555460-M
  • Product descriptionRho Inhibitor, Rhosin - Calbiochem
  • Packaging25mg
  • Price$242
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Crysdot CD31004418 Rhosin 98+% 10mg $347 2021-12-16 Buy
Crysdot CD31004418 Rhosin 98+% 5mg $243 2021-12-16 Buy
CSNpharm CSN17515 Rhosin 5mg $336 2021-12-16 Buy
Sigma-Aldrich 555460-M Rho Inhibitor, Rhosin - Calbiochem 25mg $242 2024-03-01 Buy

Properties

Density :1.38±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :Soluble in DMSO
form :Orange brown powder
pka :12.00±0.46(Predicted)
color :orange-brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ChEBI: Rhosin is a D-tryptophan derivative obtained by formal condensation of the carboxy group of D-tryptophan with the amino group of (quinoxalin-6-yl)methylidenehydrazide. It directly targets the Rho GEF binding domain, thereby preventing Rho from interacting with its GEFs It has a role as a RhoA inhibitor, a RhoC inhibitor and an antineoplastic agent. It is a D-tryptophan derivative, a quinoxaline derivative and a hydrazone.