Rimonabant suppliers
Rimonabant
- CAS:
- 168273-06-1
- MF:
- C22H21Cl3N4O
- MW:
- 463.79
Suppliers by country/region
Company Type
Properties
- Melting point:
- 154.7 °C
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- RT
- solubility
- Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
- pka
- 11.31±0.20(Predicted)
- form
- solid
- color
- White
- Stability:
- Stable for 1 year from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
- InChI
- InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
- InChIKey
- JZCPYUJPEARBJL-UHFFFAOYSA-N
- SMILES
- N1(C2=CC=C(Cl)C=C2Cl)C(C2=CC=C(Cl)C=C2)=C(C)C(C(NN2CCCCC2)=O)=N1
- CAS DataBase Reference
- 168273-06-1(CAS DataBase Reference)
Safety Information
- Symbol(GHS)
GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H410-H372
- Precautionary statements
- P260-P264-P270-P314-P501-P273-P391-P501
Use
Rimonabant is a first-in-class drug launched as an oral treatment for obesity, and its mechanism of action involves the selective antagonism of cannabinoid type 1 (CB1) receptor. It is specifically indicated as an adjunct to diet and exercise for the treatment of obese patients (body mass index [BMI]≥30 kg/m2), or overweight patients (BMI＞27 kg/m2) with associated risk factors such as type 2 diabetes or dyslipidemia. Additionally, rimonabant is currently under development as a treatment for nicotine dependence. The CB1 and CB2 receptors, along with their endogenous ligands, constitute the endocannabinoid system. The CB1 receptor is expressed in the brain, adipose tissue, and several peripheral organs; the CB2 receptor is predominantly expressed in immune cells. Activation of the CB1 receptor in the CNS is associated with appetite stimulation and the modulation of brain reward mechanism, whereas activation in the periphery favors metabolic processes that lead to hepatic lipogenesis and impaired glucose homeostasis. Rimonabant acts by selectively blocking the action of central and peripheral CB1 receptors, thereby reducing food intake and improving lipid and glucose metabolism.
180 supplier list of "Rimonabant"
$10.00/ 1kg
- Product Name:Rimonabant
- Products Intro:Purity: 99%|Package: 1kg;10.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1-Octadecanol,AMP 95,Polyisobutylene,tetramisole hcl,Ivermectin
- Product Name:Rimonabant
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,phenylacetamide
- Product Name:Rimonabant
- Products Intro:Purity: 99% | Package: 5kg;99USD|10kg;88USD|25kg;66USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Tirzepatide,Semaglutide,Liraglutide,Sodium hydroxide,Calcium hypochlorite
- Product Name:Rimonabant
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
$8.00/ 1kg
- Product Name:Rimonabant
- Products Intro:Purity: 98% | Package: 1kg;8USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:Rimonabant
- Products Intro:Purity: >98% | Package: 250 mg | CustNote: Reach out to us for more information about custom solutions.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:rimonabant
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Rimonabant；SR141716
- Products Intro:Purity: 99.91% | Package: 10mg;42USD|25mg;83USD|50mg;132USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:RIMONABAND
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
- Product Name:Rimonabant
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials