Paliperidone suppliers
Paliperidone
- CAS:
- 144598-75-4
- MF:
- C23H27FN4O3
- MW:
- 426.48
Suppliers by country/region
Company Type
Properties
- Melting point:
- 158-160°C
- Boiling point:
- 612.3±65.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble2mg/mL, clear (warmed)
- pka
- 13.00±0.60(Predicted)
- form
- powder
- color
- white to brown
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
- InChI
- InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3
- InChIKey
- PMXMIIMHBWHSKN-UHFFFAOYSA-N
- SMILES
- C12C(O)CCCN1C(=O)C(CCN1CCC(C3C4=C(ON=3)C=C(F)C=C4)CC1)=C(C)N=2
- CAS DataBase Reference
- 144598-75-4(CAS DataBase Reference)
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P301+P310
- Hazard Codes
- T,F
- Risk Statements
- 25-39/23/24/25-23/24/25-11
- Safety Statements
- 45-36/37-16
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- UV1164720
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29349990
- Hazardous Substances Data
- 144598-75-4(Hazardous Substances Data)
- Toxicity
- rat,LD50,oral,65mg/kg (65mg/kg),Drug Development Research. Vol. 33, Pg. 399, 1994.
Use
Paliperidone, (±)-3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one(Invega), is essentially insoluble in water and is available asextended-release tablets. Paliperidone is delivered at a constantrate using an osmotic drug release device (OsmoticRelease Oral Systems [OROS]). The absolute bioavailabilityof paliperidone is 28%, and studies in healthy subjects on ahigh-fat, high-calorie meal showed an increase in AUC.Paliperidone is 74% bound to plasma proteins. After a single,1-mg dose of C-paliperidone, 59% of the dose was excretedin the urine as unchanged drug, and 32% of the dose was recoveredas metabolites. Most of the drug (80%) is excreted bythe kidneys. Paliperidone is metabolized by dealkylation, hydroxylation,dehydrogenation, and scission of the benzoxazolering. None of these metabolic pathways account for morethan 10% of the dose. The terminal elimination half-life ofpaliperidone is 23 hours.
443 supplier list of "Paliperidone"
- Product Name:Paliperidone
- Products Intro:Purity: 99% HPLC | Package: 5KG;1KG
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: Escitalopram Oxalate,Amisulpride,Ipratropium Bromide,Tiotropium Bromide Monohydrate,Eltrombopag Olamine
$65.00-650.00 / 1kg
- Product Name:Paliperidone
- Products Intro:Purity: 0.99|Package: 1kg;65.00;USD|10kg;650.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Fine Chemical,API,Raw Material,Pharmaceutical Compounds,Others
$0.00-0.00 / 1Kg/Bag
- Product Name:Paliperidone
- Products Intro:Purity: 0.99 | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: APIs,pharmaceutical intermediates,health and food supplements,cosmetic raw materials,herbal extracts
$0.00/ 1kg
- Product Name:Paliperidone
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
$0.00/ 1g
- Product Name:Paliperidone
- Products Intro:Purity: More Than 99% | Package: 1g
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical Chemicals,Apis,Pharmaceutical Intermediates,Electronic Chemicals,OLED Intermediates
- Product Name:Paliperidone
- Products Intro:Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
- Product Name:PALIPERIDONE
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Paliperidone
- Products Intro:Purity: as in COA | Package: as customers' requirements
- Company Type: Trader
- Country/Region: CHINA
$3.00/ 3KG
- Product Name:Paliperidone
- Products Intro:Purity: 99% | Package: 3KG;3USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:Paliperidone
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Photoinitiatorsrs,Perfluroalkyl additives,Fluoronated chemicals,Pharmaceutical intermediates,UV absorber and monomerss