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[1,4]????-2-?

[1,4]????-2-?
[1,4]????-2-? ??? ???
?? ??:
99822-50-1
???:
[1,4]????-2-?
???(??):
[1,4]????-2-?
???:
[1,4]Diazepan-2-one
???(??):
1,4-diazapen-2-one;1,4-Diazapan-2-one;1,4-diazacycloheptan-2-one;Perhydro-1,4-diazepin-2-one;hexahydro-2H-1,4-Diazepin-2-one;1,4-diazepan-2-one hydrochloride;2H-1,4-Diazepin-2-one, hexahydro-;1,4-diazepan-2-one(SALTDATA: FREE);1-Piperazinecarboxylicacid,4-(3-bromopropyl)-,1,3-dimethylethylester
CBNumber:
CB91501000
???:
C5H10N2O
??? ??:
114.15
MOL ??:
99822-50-1.mol

[1,4]????-2-? ??

???
86-88 °C(Solv: acetone (67-64-1))
?? ?
166-168 °C(Press: 2 Torr)
??
1.012±0.06 g/cm3(Predicted)
?? ??
2-8°C(protect from light)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
15.88±0.20(Predicted)
??
???
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
HS ?? 2933790090
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

[1,4]????-2-? C??? ??, ??, ??

??

1,4-Diazepan-2-one is used in preparation of substituted MEK inhibitors and therapeutic uses thereof.

[1,4]????-2-? ?? ?? ? ???

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[1,4]????-2-? ?? ??

???( 65)?? ??
??? ?? ??? ?? ?? ? ??
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