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4-(Trifluoromethyl)benzophenone

4-(Trifluoromethyl)benzophenone ??? ???
?? ??:
728-86-9
???:
4-(Trifluoromethyl)benzophenone
???(??):
11β-HSD1-IN-7;Phenyl(4-(trifluoromethyl);P-TRIFLUOROMETHYL BENZOPHENONE;4'-Trifluoromethylbenzophenone;4-(TRIFLUOROMETHYL)BENZOPHENONE;4-(Trifluoromethyl)benzophenone97%;4-(TRIFLUOROMETHYL)BENZOPHENONE 97%;4-(Trifluoromethyl)benzophenone, 98+%;Phenyl[4-(trifluoromethyl)phenyl] ketone;PHENYL[4-(TRIFLUOROMETHYL)PHENYL]METHANONE
CBNumber:
CB8765628
???:
C14H9F3O
??? ??:
250.22
MOL ??:
728-86-9.mol

4-(Trifluoromethyl)benzophenone ??

???
114-116 °C(lit.)
?? ?
309.2±42.0 °C(Predicted)
??
1.2778 (estimate)
?? ??
Sealed in dry,Room Temperature
??? ??
??? ??
??
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BRN
1879572
InChI
InChI=1S/C14H9F3O/c15-14(16,17)12-8-6-11(7-9-12)13(18)10-4-2-1-3-5-10/h1-9H
InChIKey
OHTYZZYAMUVKQS-UHFFFAOYSA-N
SMILES
C(C1=CC=CC=C1)(C1=CC=C(C(F)(F)F)C=C1)=O
CAS ??????
728-86-9(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-37/39-24/25
WGK ?? 3
?? ?? IRRITANT
HS ?? 29147000
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

4-(Trifluoromethyl)benzophenone C??? ??, ??, ??

??? ??

OFF-WHITE TO BEIGE CRYSTALLINE SOLID

Synthesis

A solution of diphenylmethanol (1 mmol), NBS (1.3equiv.), KOAc (1.5 equiv.) H2O (1.5 mL), and CH2Cl2 (0.5mL) was magnetically stirred in 25 mL flask at room temperaturefor 10 h. The reaction mixture was added into water(10 mL), and extracted with EtOAc (3 × 10 mL). The combinedEtOAc extracts were dried over anhydrous MgSO4,filtrated, and then the solvent was removed under reducedpressure. The residue was purified by the flash columnchromatography on silica gel with PE or PE/EtOAc as theeluent to obtain the desired product 4-(Trifluoromethyl)benzophenone.
4-(TRIFLUOROMETHYL)BENZOPHENONE

4-(Trifluoromethyl)benzophenone ?? ?? ? ???

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4-(Trifluoromethyl)benzophenone ?? ??

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4-(Trifluoromethyl)benzophenone ?? ??:

???? 2-FLUORO-4-(TRIFLUOROMETHYL)BENZOPHENONE,2-Fluoro-4-(trifluoromethyl)benzophenone97%,2-Fluoro-4-(trifluoromethyl)benzophenone 97% 4-(Trifluoromethyl)benzophenone 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOPHENONE 3,4'-Bis(trifluoromethyl)benzophenone98%,3,4'-BIS(TRIFLUOROMETHYL)BENZOPHENONE,3,4'-DI(TRIFLUOROMETHYL)BENZOPHENONE,3,4'-Bis(trifluoromethyl)benzophenone 98% 2-(TRIFLUOROMETHYL)BENZOPHENONE,2-(Trifluoromethyl)benzophenone98%,2-(TRIFLUOROMETHYL)BENZOPHENONE 99% 4-FLUORO-3-(TRIFLUOROMETHYL)BENZOPHENONE 3-(Trifluoromethyl)benzophenone98%,3-(TRIFLUOROMETHYL)BENZOPHENONE,3-(TRIFLUOROMETHYL)BENZOPHENONE 99% 3,3',5,5'-Tetrakis(trifluoromethyl)benzophenone 97%,3,3',5,5'-TETRAKIS(TRIFLUOROMETHYL)BENZOPHENONE,3,3',5,5'-Tetrakis(trifluoromethyl)benzophenone97% 2-Fluoro-6-(trifluoromethyl)benzophenone97%,2-FLUORO-6-(TRIFLUOROMETHYL)BENZOPHENONE 3,3'-BIS(TRIFLUOROMETHYL)BENZOPHENONE, 9 8%,3,3'-Bis(trifluoromethyl)benzophenone 98%,3,3'-BIS(TRIFLUOROMETHYL)BENZOPHENONE,3,3'-DI(TRIFLUOROMETHYL)BENZOPHENONE 2,2'-DICHLORO-5,5'-BIS-TRIFLUOROMETHYL-BENZOPHENONE 3-FLUORO-5-(TRIFLUOROMETHYL)BENZOPHENONE 2-Chloro-5-(trifluoromethyl)benzophenone 97%,2-Chloro-5-(trifluoromethyl)benzophenone97%,2-CHLORO-5-(TRIFLUOROMETHYL)BENZOPHENONE 2-FLUORO-3-(TRIFLUOROMETHYL)BENZOPHENONE,2-Fluoro-3-(trifluoromethyl)benzophenone 97%,2-Fluoro-3-(trifluoromethyl)benzophenone97% 2-Fluoro-5-(trifluoromethyl)benzophenone 97%,2-FLUORO-5-(TRIFLUOROMETHYL)BENZOPHENONE,2-Fluoro-5-(trifluoromethyl)benzophenone97% 3,5-Bis(trifluoromethyl)benzophenone 97%,3,5-BIS(TRIFLUOROMETHYL)BENZOPHENONE,3,5-DI(TRIFLUOROMETHYL)BENZOPHENONE METHOXYPHENONE
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