Methylglucamine antimonate
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Methylglucamine antimonate ??
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- Refrigerator, Under inert atmosphere
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- ?? DMSO(?? ???, ??? ??), ?? ??(?? ?? ???, ??)
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- InChI
- InChI=1/C7H17NO5.3O.Sb/c1-8-2-4(10)6(12)7(13)5(11)3-9;;;;/h4-13H,2-3H2,1H3;;;;/q;;;;-1/p+1/t4-,5+,6+,7+;;;;/s3
- InChIKey
- JLGCKKAHTCRITP-GZLWXHMYNA-O
- SMILES
- [C@@H](O)([C@@H](O)CNC)[C@H](O)[C@H](O)CO.[Sb-](=O)(=O)=O.[H+] |&1:0,2,7,9,r|
- CAS ??????
- 133-51-7(CAS DataBase Reference)
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Methylglucamine antimonate C??? ??, ??, ??
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In the synthesis of surface active agents, pharmaceuticals, dyes.Pharmaceutical Applications
N-Methylglucamine antimonate; methylaminoglucitol antimonate. The SbV content varies around 28% between batches. The major moieties are SbV–ligand complexes which are zwitterionic in solution. The activity, pharmacology and toxicology are similar to those of sodium stibogluconate, with which it is essentially interchangeable.Clinical Use
Treatment of visceral and cutaneous leishmaniasisStudies in Central and South America have indicated that the combination with interferon-γ is effective in the treatment of visceral and cutaneous leishmaniasis cases unresponsive to antimony alone.
Methylglucamine antimonate ?? ?? ? ???
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Methylglucamine antimonate ?? ??
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