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(3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one ??? ???
?? ??:
1593543-07-7
???:
(3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
???(??):
Ezetimibe-22;Ezetimibe Impurity A;(3S,4S,3’S)-Ezetimbe;(3S,4S,3''S)-Ezetimbe;(3S,4S,3'S)-Ezetimibe;(3S,4S,3’S)-Ezetimibe;Ezetimibe Impurity SSS;Ezetimibe (SSS) Isomersy;Ezetimibe Impurity 2(SSS);Ezetimium cloth impurity SSS
CBNumber:
CB82735588
???:
C24H21F2NO3
??? ??:
409.43
MOL ??:
1593543-07-7.mol

(3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one ??

???
>72°C (dec.)
?? ?
654.9±55.0 °C(Predicted)
??
1.334±0.06 g/cm3(Predicted)
?? ??
-20°C Freezer
???
DMSO(?? ???), ???(?? ???)
?? ?? (pKa)
9.72±0.30(Predicted)
??? ??
??
??? ??
??? ??
??
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??

(3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one C??? ??, ??, ??

??

(3S,4S,3’S)-Ezetimbe is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor.

(3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one ?? ?? ? ???

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(3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one ?? ??

???( 76)?? ??
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