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2-???????,α-????-α-2-???-,(3R)-1-??????[2.2.2]??-3-?????

2-???????,α-????-α-2-???-,(3R)-1-??????[2.2.2]??-3-?????
2-???????,α-????-α-2-???-,(3R)-1-??????[2.2.2]??-3-????? ??? ???
?? ??:
320347-97-5
???:
2-???????,α-????-α-2-???-,(3R)-1-??????[2.2.2]??-3-?????
???(??):
2-???????,α-????-α-2-???-,(3R)-1-??????[2.2.2]??-3-?????
???:
2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester
???(??):
GYDFTKNRHZMENP-ZDUSSCGKSA-N;Tiotropium Bromide Impurity 2;Aclidinium Bromide Impurity 5;Tiotropium bromide Impurity 18;(R)-Quinucldin-3-yl hydroxybis(2-thienyl)acetate;(R)-quinuclidin-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate;2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester;2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester-5
CBNumber:
CB82668165
???:
C17H19NO3S2
??? ??:
349.46
MOL ??:
320347-97-5.mol

2-???????,α-????-α-2-???-,(3R)-1-??????[2.2.2]??-3-????? ??

???
180℃ (isopropyl ether )
?? ?
513.3±50.0 °C(Predicted)
??
1.40±0.1 g/cm3(Predicted)
?? ?? (pKa)
10.33±0.29(Predicted)

??

2-???????,α-????-α-2-???-,(3R)-1-??????[2.2.2]??-3-????? C??? ??, ??, ??

??

(R)-3-Quinuclidinyl di(2-thienyl)glycolate acts as a potent and long-acting muscarinic antagonist with minimal systemic exposure after inhalation. Used in the treatment of chronic obstructive pulmonary disease.

2-???????,α-????-α-2-???-,(3R)-1-??????[2.2.2]??-3-????? ?? ?? ? ???

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2-???????,α-????-α-2-???-,(3R)-1-??????[2.2.2]??-3-????? ?? ??

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