ChemicalBook >?? ???? >6,11-?-O-?????????

6,11-?-O-?????????

6,11-?-O-????????? ??? ???

?? ??:: 81103-14-2

???:: 6,11-?-O-?????????

???(??):: 6,11-?-O-?????????

???:: 6,11-Di-O-Methyl ErythroMycin

???(??):: 11-O-MethylclarithroMycin;Clarithromycin EP Impurity E;6,11-Di-O-Methyl ErythroMycin;Erythromycin, 6,11-di-O-methyl-;Clarithromycin USP Related Compound A;Clarithromycin EP Impurity E (USP RC A);Clarithromycin Impurity 5(Clarithromycin EP Impurity E);Clarithromycin EP Impurity E/ Clarithromycin Related Compound A (6,11-Di-O-methylerythromycin A);(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro;Clarithromycin EP Impurity E/3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,12-di

CBNumber:: CB82550839

???:: C39H71NO13

??? ??:: 761.98

MOL ??:: 81103-14-2.mol

?? ?? 66

6,11-?-O-????????? ??

???: 252-257 °C(Solv: dichloromethane (75-09-2); ethyl ether (60-29-7))

?? ?: 808.6±65.0 °C(Predicted)

??: 1.16±0.1 g/cm3(Predicted)

?? ??: -20°C Freezer, Under inert atmosphere

???: ?????(??), DMSO(??, ??), ???(??, ??)? ???

?? ?? (pKa): 12.96±0.70(Predicted)

??: ???? ?????

??

HS ??	2932206000

6,11-?-O-????????? C??? ??, ??, ??

??

6,11-Di-O-methyl Erythromycin (Clarithromycin EP Impurity E) is a Di-O-alkyl Erythromycin (E649950) is an impurity of Clarithromycin (C559750). Clarithromycin impurity E per British Pharmacopoeia.

6,11-?-O-????????? ?? ?? ? ???

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6,11-?-O-????????? ?? ??

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???	??	???	??	?? ?	??
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6,11-?-O-????????? ?? ??:

N-Desmethyl Clarithromycin (9E)-Oxime Clarithromycin Impurity Q (10 mg) (N-oxide clarithromycin) 3-O-Decladinosyl-6-O-Methylerythronolide A Clarithromycin Impurity H 3-O-De(2,6-dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)-8,9,10,11-tetradehydro-9-deoxo-11,12-dideoxy-9,12-epoxy-6-O-MethylerythroMycin N-DEMETHYL ERYTHROMYCIN A ERYTHROMYCIN OXIME (10E)-10,11-Didehydro-11-deoxy-6-O-MethylerythroMycin Clarithromycin Clarthromycin EP Impurity B 4'',6-Di-O-MethylerythroMycin Clarithromycin (9Z)-O-Methyloxime ClarithroMycin EP IMpurity F N-Desmethyl Clarithromycin ClarithroMycin IMpurity G 16-hydroxyclarithromycin CLARITHROMYCIN OXIME Clarithromycin (9Z)-Oxime

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