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2,4,5,6-?????????? ???

2,4,5,6-?????????? ???
2,4,5,6-?????????? ??? ??? ???
?? ??:
5392-28-9
???:
2,4,5,6-?????????? ???
???(??):
2,4,5,6-?????????????;??????????????;2,4,5,6-?????????? ????
???:
Pyrimidinetetramine sulfate
???(??):
2,4,5,6-Tetraaminopyrimidine sulfate;2,4,5,6-TETRAAMINIOPYRIMIDINE SULFATE;5329-28-9;TETRAAMINOPYRIMIDINE SULFATE;2,4,5,6-Tetramino Pyridine Sulfate;PyriMidine-2,4,5,6-tetraaMine sulfate;NSC 3277;NSC 227862;Hc Red 16;JACS-5392-28-9
CBNumber:
CB8170253
???:
C4H10N6O4S
??? ??:
238.22
MOL ??:
5392-28-9.mol
MSDS ??:
SDS

2,4,5,6-?????????? ??? ??

???
>300 °C(lit.)
?? ??
Sealed in dry,Room Temperature
???
DMSO(?? ???, ??), ?(?? ??, ??)
??? ??
??? ??
??
????? ????
???
?? ???
BRN
3785189
InChIKey
MQEFDQWUCTUJCP-UHFFFAOYSA-N
CAS ??????
5392-28-9(CAS DataBase Reference)
EPA
Pyrimidinetetramine, sulfate (1:1) (5392-28-9)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 22-24/25-37/39-26-36
WGK ?? 3
RTECS ?? UV9738000
TSCA Yes
HS ?? 29335990
???? ?? 2001-3-1760
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.
NFPA 704
1
2 0

2,4,5,6-?????????? ??? MSDS


2,4,5,6-Tetraaminopyrimidine sulfate

2,4,5,6-?????????? ??? C??? ??, ??, ??

??? ??

Light yellow crystal powder

??

2,4,5,6-Tetraaminopyrimidine Sulfate is an intermediate for the synthesis of the antitumor drugs methotrexate and fludarabine.

Purification Methods

Purify the salt by recrystallisation from H2O, 2N H2SO4 (20 parts, 67% recovery) or 0.1N H2SO4 (40 parts, 62% recovery), and dried in air. [UV: Konrad & Pfleiderer Chem Ber 103 722 1970, Malletta et al. J Am Chem Soc 69 1814 1947, Cavalieri et al. J Am Chem Soc 70 3875 1948, Beilstein 25 H 423, 25 III/IV 3106.]

2,4,5,6-?????????? ??? ?? ?? ? ???

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2,4,5,6-?????????? ??? ?? ??

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2,4,5,6-?????????? ??? ?? ??:

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