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Epirubicin

Epirubicin ??? ???
?? ??:
56420-45-2
???:
Epirubicin
???(??):
(8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione;imi28;WP 697;epi-dx;4'-Epi-DX;NSC 256942;EPIRUBICIN;Pidorubicin;Epirubicina;Farmarubicin
CBNumber:
CB8113751
???:
C27H29NO11
??? ??:
543.52
MOL ??:
56420-45-2.mol

Epirubicin ??

?? ?
617.77°C (rough estimate)
??
1.3783 (rough estimate)
???
1.6400 (estimate)
?? ??
Store at -20°C
???
DMSO? ???
??? ??
Solid
?? ?? (pKa)
7.35±0.60(Predicted)
??
Orange to red

??

?? ?? ??? 56420-45-2(Hazardous Substances Data)
?? LD50 intravenous in dog: 2mg/kg

Epirubicin C??? ??, ??, ??

??

Epirubicin is a cell permeable Topo II inhibitor.

??

ChEBI: An anthracycline that is the 4'-epi-isomer of doxorubicin.

Epirubicin ?? ?? ? ???

???

?? ??


Epirubicin ?? ??

???( 188)?? ??
??? ?? ??? ?? ?? ? ??
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