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PF-06446846

PF-06446846 ??? ???
?? ??:
1632250-49-7
???:
PF-06446846
???(??):
PF-6446846;PF-06446846;PF-06446846, 10 mM in DMSO;Benzamide, N-(3-chloro-2-pyridinyl)-N-(3R)-3-piperidinyl-4-(3H-1,2,3-triazolo[4,5-b]pyridin-3-yl)-;(R)-4-(3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)-N-(3-chloropyridin-2-yl)-N-(piperidin-3-yl)benzamide;Threonine proteases,PF06446846,Inhibitor,80S ribosome,Selective,PF 06446846,Ser/Thr Protease,Serine proteases,Rat bone marrow,Huh7,inhibit,Serine endopeptidases,PF-06446846
CBNumber:
CB74668360
???:
C22H20ClN7O
??? ??:
433.89
MOL ??:
1632250-49-7.mol

PF-06446846 ??

?? ?
655.5±65.0 °C(Predicted)
??
1.46±0.1 g/cm3(Predicted)
?? ??
Store at -20°C
???
DMSO: 87 mg/mL (200.51 mM);Ethanol: 87 mg/mL (200.51 mM)
?? ?? (pKa)
8.69±0.10(Predicted)
???
Water: Insoluble

??

PF-06446846 C??? ??, ??, ??

PF-06446846 ?? ?? ? ???

???

?? ??

PF-06446846 ?? ??

???( 16)?? ??
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