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??????????-3

??????????-3
??????????-3 ??? ???
?? ??:
827306-88-7
???:
??????????-3
???(??):
??????????-3;N2-???-L-?????-L-????-L-?????
???:
Acetyl tetrapeptide-3
???(??):
Ac-KGHK;capixyl;Ac-KGHK-NH2;Ac-Lys-Gly-His-Lys;Acetyl Tetrapeptide-3;N2-Acetyl-L-lysylglycyl-L;acetyl tetrapeptide-3/capixyl;Acetyl Tetrapeptide-4, Capixyl;Acetyl Tetrapeptide-3/Capixyl-3;TIANFUCHEM--827306-88-7---C22H39N9O5
CBNumber:
CB73052023
???:
C22H39N9O5
??? ??:
509.6
MOL ??:
827306-88-7.mol

??????????-3 ??

?? ?
1075.4±65.0 °C(Predicted)
??
1.250±0.06 g/cm3(Predicted)
?? ??
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
???
DMF: 14mg/ml DMSO: 10mg/ml ???: 10mg/ml PBS(pH 7.2): 10mg/ml
?? ?? (pKa)
13.35±0.46(Predicted)
??? ??
??
??
Off-white to light yellow
InChIKey
RRJOMESUBQAYOA-BZSNNMDCSA-N
SMILES
C(N)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CNC(=O)[C@H](CCCCN)NC(C)=O
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321 (…) ??? ???.
P330 ?? ?????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
P403+P233 ??? ??? ? ?? ?? ??? ???? ?????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
0
2 0

??????????-3 C??? ??, ??, ??

??

Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 μM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin explants.

Biological Functions

Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 μM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin explants.

???

There are no documented adverse side effects to using acetyl tetrapeptide-3 topically (on the skin), but it can irritate your eyes.

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???( 206)?? ??
??? ?? ??? ?? ?? ? ??
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??????????-3 ?? ??:

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