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Z-DEVD-FMK

Z-DEVD-FMK ??? ???
?? ??:
210344-95-9
???:
Z-DEVD-FMK
???(??):
S7312;CS-1505;CTK8E8674;abs812077;Z-DEVD-FMK;AG-B-56189;Z-DEVD-FMK 抑制劑;CASPASE-3, INHIBITOR;CASPASE-3 INHIBITOR2;Z-DEVD-FMK USP/EP/BP
CBNumber:
CB6453635
???:
C30H41FN4O12
??? ??:
668.66
MOL ??:
Mol file
MSDS ??:
SDS

Z-DEVD-FMK ??

?? ?
914.2±65.0 °C(Predicted)
??
1.260±0.06 g/cm3(Predicted)
?? ??
Inert atmosphere,Store in freezer, under -20°C
???
DMSO/DMF: ≥20 mM
?? ?? (pKa)
10.26±0.46(Predicted)
??? ??
???? ?? ??? ??
??
White to off-white

??

WGK ?? 3

Z-DEVD-FMK C??? ??, ??, ??

??

Z-DEVD-FMK is an irrversible caspase-3 inhibitor used as an anaesthetic agent. In addition, it is proposed to increase the longevity of platelet storage.

?? ??

A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 μg/75 μl) solution of Z-DEVD-FMK (Cat. No. 264156) in DMSO is also available.

???? ??

Cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo .

Z-DEVD-FMK ?? ?? ? ???

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Z-DEVD-FMK ?? ??

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