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N-?????????

N-?????????
N-????????? ??? ???
?? ??:
1343498-72-5
???:
N-?????????
???(??):
N-?????????
???:
N-Desmethyl Regorafenib
???(??):
BAY751098;BAY 751098;BAY-751098;Relebactam D4;UNII-58I22S7HYD;Regorafenib impurity O;N-Desmethyl Regorafenib;Regorafenib Impurity 53;Regorafenib metabolite M4;Regorafenib M-4 metabolite
CBNumber:
CB63049901
???:
C20H13ClF4N4O3
??? ??:
468.79
MOL ??:
1343498-72-5.mol

N-????????? ??

???
>195°C (dec.)
?? ?
496.8±45.0 °C(Predicted)
??
1.552±0.06 g/cm3(Predicted)
?? ??
-20°C Freezer
???
DMSO(?? ???), ???(?? ???)
?? ?? (pKa)
12.06±0.70(Predicted)
??? ??
??
??? ??
??? ??
??
?? ????? ?? ?????

??

N-????????? C??? ??, ??, ??

??

N-Desmethyl Regorafenib is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.

N-????????? ?? ?? ? ???

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