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LGD-2226

LGD-2226 ??? ???
?? ??:
328947-93-9
???:
LGD-2226
???(??):
LGD-2226;LGD-2226 (LGD2226);6-[Bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-2(1H)-quinolinone;6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1H-quinolin-2-one;2(1H)-Quinolinone, 6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-;6-[Bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-2(1H)-quinolinone
CBNumber:
CB62750752
???:
C14H9F9N2O
??? ??:
392.22
MOL ??:
328947-93-9.mol
MSDS ??:
SDS

LGD-2226 ??

???
187-190°C
?? ?
364.4±42.0 °C(Predicted)
??
1.526±0.06 g/cm3(Predicted)
?? ??
-20°C Freezer, Under inert atmosphere
???
DMSO(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
9.88±0.70(Predicted)
??
?? ????? ?? ?????
BRN
10716241
InChI
InChI=1S/C14H9F9N2O/c15-12(16,17)5-25(6-13(18,19)20)7-1-2-10-8(3-7)9(14(21,22)23)4-11(26)24-10/h1-4H,5-6H2,(H,24,26)
InChIKey
ULBPQWIGZUGPHU-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(N(CC(F)(F)F)CC(F)(F)F)C=C2)C(C(F)(F)F)=CC1=O
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 48/22
WGK ?? 3
RTECS ?? VC8275240
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H373 ??? ?? ?? ???? ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ?? ?? ???? ?? - ?? ?? ?? 2 ?? P260, P314, P501
??????:
P260 ??·?·??·???·??·...·????? ???? ???.
P314 ???? ??? ???? ??·??? ????.
P501 ...? ??? / ??? ?? ???.

LGD-2226 C??? ??, ??, ??

??

LGD-2226 is an orally active potent and selective androgen receptor modulator used in the treatment of muscle wasting and osteoporosis. Show to have an anabolic effect on muscle and bone tissue.

LGD-2226 ?? ?? ? ???

???

?? ??

LGD-2226 ?? ??

???( 46)?? ??
??? ?? ??? ?? ?? ? ??
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