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?????? ??? ???
?? ??:
32747-08-3
???:
??????
???(??):
??????
???:
Glycohyocholic acid
???(??):
N-hyocholoylglycine;Glycohyocholic acid;Glycohyocholic acid (GHCA);Hyocholic acid-glycine conjugate;N-(3α,6α,7α-Trihydroxy-24-oxo-5β-cholan-24-yl)glycine;N-(24-Oxo-3α,6α,7α-trihydroxy-5β-cholan-24-yl)glycine;Glycine, N-[(3α,5β,6α,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]-;5β-CHOLANIC ACID-3α, 6α, 7α-TRIOL N-(CARBOXYMETHYL)-AMIDE SODIUM SALT;2-[[(4R)-4-[(3R,5R,6R,7S,8S,9S,10R,13R,14S,17R)-3,6,7-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
CBNumber:
CB62283944
???:
C26H43NO6
??? ??:
465.63
MOL ??:
32747-08-3.mol
MSDS ??:
SDS

?????? ??

?? ?
673.4±55.0 °C(Predicted)
??
1.213±0.06 g/cm3(Predicted)
?? ??
Store at -20°C
???
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
??? ??
??? ??
?? ?? (pKa)
3.58±0.10(Predicted)
??
Off-white to light yellow

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Glycohyocholic acid (GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid . GHCA is upregulated 6.6-fold in the serum of patients with cirrhosis induced by hepatitis C virus (HCV) compared to healthy controls. Plasma levels of GHCA increase in patients who are no longer diabetic following gastric bypass surgery.

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Glycohyocholic Acid is a bile salt.

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