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???04-6790

???04-6790
???04-6790 ??? ???
?? ??:
202466-68-0
???:
???04-6790
???(??):
???04-6790
???:
RO 04-6790
???(??):
Ro 04 6790,Ro 046790;4-amino-N-[2,6-bis(methylamino)pyrimidin-4-yl]benzenesulfonamide;4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]-benzenesulfonamide;BenzenesulfonaMide, 4-aMino-N-[2,6-bis(MethylaMino)-4-pyriMidinyl]-;4-amino-n-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide dihydrobromide
CBNumber:
CB5972319
???:
C12H16N6O2S
??? ??:
308.36
MOL ??:
202466-68-0.mol

???04-6790 ??

?? ?
595.8±60.0 °C(Predicted)
??
1.495
?? ??
Store at -20°C
???
DMSO: >10mg/mL
??? ??
??
??? ??
??? ??
?? ?? (pKa)
9.16±0.50(Predicted)
??
???

??

??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36
WGK ?? 3
RTECS ?? DA9462500

???04-6790 C??? ??, ??, ??

??

Ro 04-6790 is a SR-6 antagonist.

???? ??

Potent and selective 5-HT 6 receptor antagonist (pK i values are 7.26 and 7.35 at rat and human 5-HT 6 receptors respectively). Displays no affinity at a range of other receptors (IC 50 > 10 μ M). Induces stretching behavior in rats in vivo .

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???04-6790 ?? ??:

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