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DEPBT

DEPBT ??? ???
?? ??:
165534-43-0
???:
DEPBT
???(??):
3-(DIETHOXYPHOSPHORYLOXY)-1,2,3-BENZOTRIAZIN-4(3H)-ONE;Diethyl (4-oxobenzo[d][1,2,3]triazin-3(4H)-yl) phosphate;DEPBT 3-(DIETHOXYPHOSPHORYLOXY)-1,2,3-BENZOTRIAZIN-4(3H)-ONE;DEPBT;4(3H)-ONE;DEPBT 25 G;DEPBT USP/EP/BP;3-(Diethoxyphosphory;Famitinib Impurity 16;3-(Diethoxyphosphoryloxy)-1,2,3-
CBNumber:
CB5767838
???:
C11H14N3O5P
??? ??:
299.22
MOL ??:
165534-43-0.mol

DEPBT ??

???
75-77°C
?? ?
382.1±25.0 °C(Predicted)
??
1.45±0.1 g/cm3(Predicted)
?? ??
Store at +2°C to +8°C.
???
almost transparency in Ethylacetate
??? ??
??
??
???
InChI
InChI=1S/C11H14N3O5P/c1-3-17-20(16,18-4-2)19-14-11(15)9-7-5-6-8-10(9)12-13-14/h5-8H,3-4H2,1-2H3
InChIKey
AJDPNPAGZMZOMN-UHFFFAOYSA-N
SMILES
P(ON1C(=O)C2=CC=CC=C2N=N1)(OCC)(OCC)=O
CAS ??????
165534-43-0(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36
WGK ?? 3
HS ?? 29339990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

DEPBT C??? ??, ??, ??

??? ??

White solid

??

DEPBT is a peptide coupling reagent used in peptide synthesis. It shows remarkable resistance to racemization.

?? ??

3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one (DEPBT) is a coupling reagent that facilitates amide bond formation and also resists racemization. It has been shown to be more effective than phosphonium and uronium coupling reagents.

DEPBT ?? ?? ? ???

???

?? ??


DEPBT ?? ??

???( 291)?? ??
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DEPBT ?? ??:

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