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3-CHLORO-5-FLUOROPHENOL

3-CHLORO-5-FLUOROPHENOL ??? ???
?? ??:
202982-70-5
???:
3-CHLORO-5-FLUOROPHENOL
???(??):
3-CHLORO-5-FLUOROPHENOL;Phenol, 3-chloro-5-fluoro-;3-Chloro-5-fluorophenol98%;3-Chloro-5-fluorophenol 98%;Phenol, 3-chloro-5-fluoro- (9CI);3-Chloro-4-fluoro-α,α,α-trifluorotoluene;3-CHLORO-5-FLUOROPHENOL ISO 9001:2015 REACH
CBNumber:
CB5273858
???:
C6H4ClFO
??? ??:
146.55
MOL ??:
202982-70-5.mol

3-CHLORO-5-FLUOROPHENOL ??

?? ?
206.0±20.0 °C(Predicted)
??
1.408±0.06 g/cm3(Predicted)
???
1.537
?? ??
Inert atmosphere,Room Temperature
??? ??
??
?? ?? (pKa)
8.01±0.10(Predicted)
??
???
???
?? ??? ????.
CAS ??????
202982-70-5(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,Xn
?? ???? ?? 20/21/22-36/37/38-22
????? 26-36/37/39
?? ?? ?? Irritant
?? ?? 8
HS ?? 2908190090
????(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 ??? ???? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H314 ??? ?? ??? ?? ??? ??? ????? ?? ????? ?? 1A, B, C ?? GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 1 ?? GHS hazard pictograms P280, P305+P351+P338, P310
H401 ????? ??? ?? ????? ?? - ?? ?? 2 P273, P501
H411 ??? ??? ?? ????? ??? ?? ????? ?? - ?? ?? 2
??????:
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P310 ?? ????(??)? ??? ????. ???? ?? ????(??)? ??? ????.
NFPA 704
1
3 0

3-CHLORO-5-FLUOROPHENOL C??? ??, ??, ??

??

3-Chloro-5-fluorophenol is used as an intermediate in organic synthesis. It plays an important role in the preparation of substituted amides as antagonists and/or inverse agonists of cannabinoid-1 receptor, substituted N-(arylmethyl)aryloxy arylcarboxamide and heteroarylcarboxamide antagonists for the PGE2 receptor EP4 for the treatment of pain, inflammation, osteoarthritis, and rheumatoid arthritis.

3-CHLORO-5-FLUOROPHENOL ?? ?? ? ???

???

?? ??


3-CHLORO-5-FLUOROPHENOL ?? ??

???( 145)?? ??
??? ?? ??? ?? ?? ? ??
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3-CHLORO-5-FLUOROPHENOL ?? ??:

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