9-Boc-3-oxa-7,9-???????[3.3.1]??
9-Boc-3-oxa-7,9-???????[3.3.1]?? ??? ???
?? ??:
1251010-45-3
???:
9-Boc-3-oxa-7,9-???????[3.3.1]??
???(??):
9-Boc-3-oxa-7,9-???????[3.3.1]??
???:
9-Boc-3-oxa-7,9-diazabicyclo[3.3.1]nonane
???(??):
9-Boc-3-oxa-7,9-diazabicyclo[3.3.1]nonane;tert-Butyl 3-oxa-7,9-diazabicyclo[3.3.1]nonane-9-carboxylate;Racemic-(1R,5S)-tert-butyl3-oxa-7,9-diazabicyclo[3.3.1]nonane-9-carboxylate;3-Oxa-7,9-diazabicyclo[3.3.1]nonane-9-carboxylic acid, 1,1-dimethylethyl ester
CBNumber:
CB52704561
???:
C11H20N2O3
??? ??:
228.29
MOL ??:
1251010-45-3.mol
9-Boc-3-oxa-7,9-???????[3.3.1]?? ??
?? ?
325.8±42.0 °C(Predicted)
??
1.108±0.06 g/cm3(Predicted)
?? ??
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
?? ?? (pKa)
8.84±0.20(Predicted)
??
?? ? ?? ??
?? ? ???? ?? (GHS)
????(GHS):
?? ?:
Warning
??·?? ??:
??
??·?? ??
?? ??
??
?? ?
?? ??
P- ??
H302
??? ???
?? ?? ?? - ??
?? 4
??
P264, P270, P301+P312, P330, P501
H315
??? ??? ???
????? ?? ?????
?? 2
??
P264, P280, P302+P352, P321,P332+P313, P362
H319
?? ?? ??? ???
?? ? ?? ?? ??? ??
?? 2A
??
P264, P280, P305+P351+P338,P337+P313P
H335
?? ???? ??? ? ??
?? ???? ?? - 1? ??;???? ??
?? 3
??
??????:
P261
??·?·??·???·??·...·????? ??? ????.
P305+P351+P338
?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
9-Boc-3-oxa-7,9-???????[3.3.1]?? C??? ??, ??, ??
??
tert-Butyl 3-oxa-7,9-diazabicyclo[3.3.1]nonane-9-carboxylate is used in preparation of substituted pyrazolopyridines as inhibitors of FGFR tyrosine kinases for treatment of FGFRs-mediated diseases.
9-Boc-3-oxa-7,9-???????[3.3.1]?? ?? ?? ? ???
???
?? ??
9-Boc-3-oxa-7,9-???????[3.3.1]?? ?? ??
???( 45)?? ??
China 39
India 2
United States 4
Global 45