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3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone

3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone ??? ???
?? ??:
491871-58-0
???:
3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone
???(??):
CS-1482;TCS PIM-1;SC 204330;TCS PIM-1 1;TCS PIM-1 1, >=98%;TCS PIM-1 1(sc-204330);SC 204330; TCS PIM 1-1;3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone;6-(5-Bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-3-pyridinecarbonitrile;3-Pyridinecarbonitrile, 6-(5-bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-
CBNumber:
CB52518751
???:
C18H11BrN2O2
??? ??:
367.2
MOL ??:
491871-58-0.mol

3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone ??

?? ?
592.6±50.0 °C(Predicted)
??
1.63±0.1 g/cm3(Predicted)
?? ??
Store at +4°C
???
insoluble in H2O; insoluble in EtOH; ≥12.8 mg/mL in DMSO
??? ??
??
??? ??
??? ??
?? ?? (pKa)
6.93±0.10(Predicted)
??
Light yellow to yellow

??

3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone C??? ??, ??, ??

??

TCS PIM-1 1 is a Pim-1 kinase inhibitor.

3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone ?? ?? ? ???

???

?? ??


3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone ?? ??

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