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OPHIOPOGONIN D

OPHIOPOGONIN D ??? ???
?? ??:
945619-74-9
???:
OPHIOPOGONIN D
???(??):
Ophiopogonin D;CAS:945619-74-9;PubChem ID: 46173859;Deacetylophiopogonin C;OPHIOPOGONIN D USP/EP/BP;Ophiopogonin D >=98% (HPLC);Deacetylophiopogonin C，OJV-V;OPHIOPOGONIN D, 10 mM in DMSO;β-D-Galactopyranoside, (1β,3β,25R)-3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-6-deoxy-;(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-Hydroxy-2-(((4R,5'R,6R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-6-yl)oxy)-6-methyl-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol
CBNumber:
CB52453416
???:
C44H70O16
??? ??:
855.03
MOL ??:
945619-74-9.mol
MSDS ??:
SDS

OPHIOPOGONIN D ??

???
263-265 °C
??
1.40
?? ??
Sealed in dry,Store in freezer, under -20°C
???
DMF:30.0(Max Conc. mg/mL);35.09(Max Conc. mM)
DMSO:30.0(Max Conc. mg/mL);35.09(Max Conc. mM)
Ethanol:15.0(Max Conc. mg/mL);17.54(Max Conc. mM)
??? ??
??
?? ?? (pKa)
13.01±0.70(Predicted)
??
White to off-white
InChIKey
FHKHGNFKBPFJCB-UWTSJSSWNA-N
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P330 ?? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
0
2 0

OPHIOPOGONIN D C??? ??, ??, ??

??

Ophiopogonin D is a natural product isolated from Radix Ophiopogon japonicus that protects the heart against doxorubicin-induced autophagic injury by reduction of both ROS generation and the disruption of the mitochondrial membrane damage.

?? ??

Ophiopogonin D is a bioactive compound that is found in Salvia miltiorrhiza. It has been shown to have hypoglycemic effects and significant cytotoxicity against tumor cells, which may be due to its ability to inhibit glucose uptake. It also causes mitochondrial membrane potential reduction, leading to the induction of apoptosis. This compound also has immunomodulatory effects. In addition, it inhibits the activation of toll-like receptors and prevents the translocation of nuclear factor-κB into the nucleus. Ophiopogonin D also has an effect on bowel disease, myocardial infarcts, and energy metabolism by inhibiting c-jun phosphorylation.

OPHIOPOGONIN D ?? ?? ? ???

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?? ??

OPHIOPOGONIN D ?? ??

???( 171)?? ??
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OPHIOPOGONIN D ?? ??:

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