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134-29-2
???:
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???(??):
O-?????????;O-?????????;O-????????
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O-ANISIDINE HYDROCHLORIDE
???(??):
c.i.37115;nci-c03747;fastredbbbase;o-AnisidineHCl;ANISIDINE HYDROCHLORIDE;2-anisidinehydrochloride;O-ANISIDINE HYDROCHLORIDE;o-anisylaminehydrochloride;2-aminoanisolehydrochloride;o-aminoanisolehydrochloride
CBNumber:
CB4471183
???:
C7H10ClNO
??? ??:
159.61
MOL ??:
134-29-2.mol
MSDS ??:
SDS

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228-230 °C
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powder to crystal
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CAS ??????
134-29-2(CAS DataBase Reference)
IARC
2A (Vol. 127)
EPA
o-Anisidine hydrochloride (134-29-2)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 36/37/38-22
????? 26-36/37/39
????(UN No.) 2811
RTECS ?? BZ6500000
HS ?? 2922.50.4000
?? ?? 6.1
???? III
?? mma-sat 10 mg/plate ENMUDM 7(Suppl 5),1,85
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H320 ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2B ?? P264, P305+P351+P338,P337+P313
H341 ???? ??? ??? ??? ??? (????? ???? ????? ???? ???? ???? ??? ?? ????? ??? ???? ??) ???? ???? ?? ?? 2 ?? P201,P202, P281, P308+P313, P405,P501
H351 ?? ??? ??? ??? (????? ?? ???? ???? ???? ??? ?? ????? ??? ???? ??) ??? ?? ?? 2 ?? P201, P202, P281, P308+P313, P405,P501
H371 ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ??(????? ?? ???? ??? ???? ???? ???? ????? ??? ????? ??) ?? ???? ?? - 2? ?? ?? 2 ?? P260, P264, P270, P309+P311, P405,P501
H373 ??? ?? ?? ???? ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ?? ?? ???? ?? - ?? ?? ?? 2 ?? P260, P314, P501
H401 ????? ??? ?? ????? ?? - ?? ?? 2 P273, P501
??????:
P201 ?? ? ?? ???? ?????.
P202 ?? ?? ?? ??? ?? ???? ??? ???? ???.
P260 ??·?·??·???·??·...·????? ???? ???.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P271 ?? ?? ??? ? ?? ???? ?????.
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P403+P233 ??? ??? ? ?? ?? ??? ???? ?????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
0
3 0

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Anisidine exists as ortho-, meta-, and paraisomers. They have characteristic amine (fishy) odors.

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o-Anisidine hydrochloride is used as a chemical intermediate in the production of numerous azo and triphenylmethane dyes and pigments (e.g., C.I. direct red 72, disperse orange 29, direct yellow 44, direct red 24, and acid red 4); in the production of pharmaceuticals, including the expectorant guaiacol; as a corrosion inhibitor for steel; and as an antioxidant for polymercaptan resins (IARC 1999, HSDB 2009).

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Gray-black crystalline solid or light gray powder. May be carcinogenic.

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Water soluble.

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O-ANISIDINE HYDROCHLORIDE reacts as an acid to neutralize bases. These neutralizations generate some heat, Usually does not react as either oxidizing agents or reducing agents but such behavior is not impossible. May catalyze organic reactions.

????

Flash point data for O-ANISIDINE HYDROCHLORIDE are not available; however, O-ANISIDINE HYDROCHLORIDE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.

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Anisidines are used in the manufacture of azo dyes; pharmaceuticals; textile-processing chemicals Incompatibilities: Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Attacks some coatings and some forms of plastic and rubber.

Carcinogenicity

o-Anisidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals.

?? ??

UN2431 Anisidines, Hazard Class: 6.1; Labels: 6.1-Poisonous materials

??? ??

Dissolve in combustible solvent (alcohols, benzene, etc.) and spray solution into furnace equipped with afterburner and scrubber, or burn spill residue on sand and soda ash absorbent in a furnace.

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