Vidarabine monophosphate
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Vidarabine monophosphate ??
- ???
- 213 °C
- ?? ?
- 798.5±70.0 °C(Predicted)
- ??
- 2.32±0.1 g/cm3(Predicted)
- ?? ??
- Store at 0°C
- ??? ??
- ??
- ?? ?? (pKa)
- 1.86±0.10(Predicted)
- ??
- ???? ?????
- ???
- 4mg/ml? ?? ???
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn,T,Xi | ||
|---|---|---|---|
| ?? ???? ?? | 20/22-40-23/24/25-36/37/38 | ||
| ????? | 37/39-24/25-45-36/37/39-22-36-26 | ||
| ????(UN No.) | 2811 | ||
| RTECS ?? | AU6204000 | ||
| ?? ?? | 6.1(a) | ||
| ???? | II | ||
| HS ?? | 29400090 | ||
| ?? | LD50 ipr-rat: 1700 mg/kg DRFUD4 4,547,79 |
Vidarabine monophosphate C??? ??, ??, ??
??
Vidarabine monophosphate, chemical name: 9-(5-O-Phosphono-beta-D-arabinofuranosyl)adenine is an anti deoxyribonucleic acid virus drug. IVidarabine triphosphate directly inhibits DNA polymerase and also acts as a chain terminator in DNA replication. An adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. It is the monophosphate ester of VIDARABINE with antiviral and possibly antineoplastic properties.??? ??
Crystalline??
Antiviral.?? ??
Vidarabine monophosphate has broad-spectrum anti-virus effect and can inhibit a variety of DNA viruses. It is mainly used to treat chronic hepatitis B and other viral infections, such as herpes zoster, herpes simplex and genital herpes. It has quick effect and clear curative effect. It is a common drug for clinical anti-virus treatment.Safety Profile
Moderately toxic byintraperitoneal route. When heated to decomposition itemits very toxic fumes of POx and NOx.Vidarabine monophosphate ?? ?? ? ???
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Vidarabine monophosphate ?? ??
???( 212)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
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Vidarabine monophosphate ?? ??:
???????? ?-2-?????? ??? ????? ??? ????? ??? ??? ????
2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-Benzofurancarboxylic acid
Sodium Monofluorophosphate
Acetyl hypoxanthine
Iodixanol
PotassiuM sodiuM Dehydroandrographolide Succinate
Vidarabine
Fludarabine phosphate
Vidarabine monophosphate
ADENINE-BETA-D-ARABINOFURANOSIDE 5'-MONOPHOSPHATE, DIAMMONIUM SALT, [2,8-3H]-
6-BENZYLOXYAMINO-9-(5-O-DIPHENYLPHOSPHONO-BETA-D-ARABINOFURANOSYL)-2-FLUORO-9H-PURINE
2-FLUORO-6-(1,2,4-TRIAZOL-1-YL)-9-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-9H-PURINE