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14(15)-EpEDE

14(15)-EpEDE ??? ???

?? ??:: 351533-80-7

???:: 14(15)-EpEDE

???(??):: 14(15)-EpEDE;ZXBWLXDDSYHRTE-QGIBGKBZSA-N;14,15-Epoxy-Eicosadienoic Acid;13-(3-pentyl-2-oxiranyl)-8(Z),11(Z)-tridecadienoic acid;8,11-Tridecadienoic acid, 13-(3-pentyl-2-oxiranyl)-, (8Z,11Z)-

CBNumber:: CB42589888

???:: C20H34O3

??? ??:: 322.48

MOL ??:: 351533-80-7.mol

?? ?? 16

14(15)-EpEDE ??

?? ?: 458.4±28.0 °C(Predicted)

??: 0.970±0.06 g/cm3(Predicted)

???: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml

?? ?? (pKa): 4.77±0.10(Predicted)

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Danger

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H225	???? ?? ? ??	??? ??	?? 2	??		P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H350	?? ??? ? ?? (????? ?? ???? ???? ???? ??? ?? ????? ??? ???? ??)	??? ??	?? 1A, 1B	??

??????:

P201	?? ? ?? ???? ?????.
P202	?? ?? ?? ??? ?? ???? ??? ???? ???.
P210	?·???·??·????? ????? - ?? ???.
P233	??? ??? ?????. ??? ??? ? ?? ?? ??? ???? ?????.
P240	??? ????? ?? ? ??????.
P241	?? ??? ??[???/??/??/...]?(?) ?????.
P242	???? ???? ?? ??? ?????
P243	??? ?? ??? ????.
P280	????/???/???/?????? ?????.
P303+P361+P353	??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P308+P313	?? ?? ??? ???? ???? ??· ??? ????.
P370+P378	?? ? ?? ?? ?? (Section 5. ??, ??? ????? ??? ???)?(?) ?????.
P403+P235	??? ? ?? ?? ???? ???? ?????.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

NFPA 704

	3
0		0

14(15)-EpEDE C??? ??, ??, ??

??

8,11,14-Eicosatrienoic acid, also known as dihomo-γ-linolenic acid , is a polyunsaturated fatty acid (PUFA) produced from γ-linolenic acid by the action of fatty acid elongases. It can be metabolized by the cyclooxygenase pathway to produce 1-series prostaglandins (PGs) (e.g., PGE₁). (±)14(15)-EpEDE is an EpEDE acid formed from 8,11,14-eicosatrienoic acid. This monoepoxide can be generated from the PUFA, in vitro, by the action of a strong oxidizing agent. Alternatively, this compound may be produced, in vivo, by epoxidation of the PUFA by cytochrome P450 epoxygenases. The biological properties of this compound are poorly understood.

14(15)-EpEDE ?? ?? ? ???

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