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R(+)-1-(PENTAFLUOROPHENYL)ETHANOL

R(+)-1-(PENTAFLUOROPHENYL)ETHANOL ??? ???
?? ??:
104371-21-3
???:
R(+)-1-(PENTAFLUOROPHENYL)ETHANOL
???(??):
R(+)-1-(PENTAFLUOROPHENYL)ETHANOL;(1R)-1-(Pentafluorophenyl)ethanol;(R)-1-(perfluorophenyl)ethan-1-ol;(1R)-1-(2,3,4,5,6-Pentafluorophenyl)ethanol;(r)-(+)-α-methyl-2,3,4,5,6-pentafluorobenzyl alcohol;R(+)-ALPHA-METHYL-2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL;Benzenemethanol, 2,3,4,5,6-pentafluoro-α-methyl-, (αR)-;(R)-(+)-1-(PENTAFLUOROPHENYL)ETHANOL, FL UKABRAND CHIRASELECT REAGENT, 99+%
CBNumber:
CB4134392
???:
C8H5F5O
??? ??:
212.12
MOL ??:
104371-21-3.mol

R(+)-1-(PENTAFLUOROPHENYL)ETHANOL ??

???
41-42 °C(lit.)
?? ?
162.9±0.0 °C(Predicted)
??
1.498±0.06 g/cm3(Predicted)
???
189 °F
?? ?? (pKa)
13.14±0.20(Predicted)
optical activity
[α]20/D +7.0±0.5°, c = 1% in pentane
BRN
5268492
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36
WGK ?? 3
F ?????? 10
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

R(+)-1-(PENTAFLUOROPHENYL)ETHANOL C??? ??, ??, ??

Purification Methods

Recrystallise the ethanol from n-pentane at -40o and sublime it at 25o/0.3mm (use ice-cooled cold finger). It has also been purified by column chromatography through Kieselgel 60 (0.063-0.2mm mesh, Merck) and eluted with EtOAc/n-hexane (1:5), then recrystallised from n-pentane and sublimed in a vacuum. It has RF on Kieselgel 60 F254 TLC foil and eluting with EtOAc/n-hexane (1:5). [Meese Justus Liebigs Ann Chem 2004 1986.]

R(+)-1-(PENTAFLUOROPHENYL)ETHANOL ?? ?? ? ???

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R(+)-1-(PENTAFLUOROPHENYL)ETHANOL ?? ??

???( 11)?? ??
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R(+)-1-(PENTAFLUOROPHENYL)ETHANOL ?? ??:

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